Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196972 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CA12CA1CA2CA9 | |
| Sulfuric Acid SCHEMBL28347706 | 0.91 | CA12 (0.37) | ALDH1A1CA12CA1CA2CA9 | |
| Dodecanol SCHEMBL5667394 | 0.83 | LMNA (0.45) | ALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL7094569 | 0.82 | ALDH1A1 (0.46) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL25028435 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL15802692 | 0.81 | CHRNB2 (0.41) | ALDH1A1LMNAHSD17B10CHRNB2CHRNA4 | |
| SCHEMBL13018204 | 0.81 | ALDH1A1 (0.44) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL22899056 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL19189532 | 0.81 | ALDH1A1 (0.40) | ALDH1A1CA12CA1CA2CA9 | |
| SCHEMBL197598 | 0.81 | CHRNB2 (0.41) | ALDH1A1LMNAHSD17B10CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428816-B1 | Method for the manufacture of dodecyl 2-(n,n-dimethylamino)-propionate | NEXMED HOLDINGS INC (US) | 2012-09-05 | — | — | EP | claimed |
| EP-1428816-A1 | Method for the manufacture of dodecyl 2-(n,n-dimethylamino)-propionate | Nexmed Holdings, Inc. (US) | 2004-06-16 | — | — | EP | claimed |
| EP-1097126-A4 | CRYSTALLINE SALTS OF DODECYL 2-(N,N-DIMETHYLAMINO)-PROPIONATE | NEXMED HOLDINGS INC (US) | 2002-08-28 | — | — | EP | claimed |
| EP-1097126-A1 | CRYSTALLINE SALTS OF DODECYL 2-(N,N-DIMETHYLAMINO)-PROPIONATE | Nexmed Holdings, Inc. (US) | 2001-05-09 | — | — | EP | claimed |
| WO-2000069809-A1 | CRYSTALLINE SALTS OF DODECYL 2-(N,N-DIMETHYLAMINO)-PROPIONATE | NEXMED HOLDINGS, INC. (US) | 2000-11-23 | — | — | WO | claimed |
| US-11246932-B2 | Prostaglandin compositions and methods for the treatment of vasospasm | NEXMED HOLDINGS, INC. (US) | 2022-02-15 | — | — | US | disclosed |
| WO-2020221826-A1 | NOVEL INDOLE-2-CARBOXAMIDES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV) | AICURIS GMBH & CO. KG (DE) | 2020-11-05 | — | — | WO | disclosed |
| WO-2020221816-A1 | NOVEL PHENYL AND PYRIDYL UREAS ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV) | AICURIS GMBH & CO. KG (DE) | 2020-11-05 | — | — | WO | disclosed |
| US-10766882-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | YUNGJIN PHARM CO., LTD. (KR) | 2020-09-08 | — | — | US | disclosed |
| EP-2646015-B1 | ACTIVE ENANTIOMER OF DODECYL 2-(N,N-DIMETHYLAMINO)-PROPIONATE | FERRING INT CENTER SA (CH) | 2020-04-22 | — | — | EP | disclosed |
| US-20190076529-A1 | PROSTAGLANDIN COMPOSITIONS AND METHODS FOR THE TREATMENT OF VASOSPASM | NEXMED HOLDINGS, INC. (US) | 2019-03-14 | — | — | US | disclosed |
| US-9975883-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | YUNGJIN PHARM. CO., LTD. (KR) | 2018-05-22 | — | — | US | disclosed |
| EP-0643128-B1 | Aqueous fabric softener composition, novel quaternary ammonium salt, and process for the preparation of said salt | KAO CORP (JP) | 1999-03-10 | — | — | EP | disclosed |
| US-5580481-A | Aqueous fabric softener composition, novel quaternary ammonium salt, and process for the preparation of said salt | KAO CORPORATION (JP) | 1996-12-03 | — | — | US | disclosed |
| US-5476597-A | Storage stability, elasticity | KAO CORPORATION (JP) | 1995-12-19 | — | — | US | disclosed |
| EP-0643128-A1 | Aqueous fabric softener composition, novel quaternary ammonium salt, and process for the preparation of said salt | Kao Corporation (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0014997-B1 | 4-ARYLOXY- AND 4-ARYLTHIO-3-PHENYLPIPERIDINE DERIVATIVES, A PROCESS FOR THE PREPARATION OF SUCH COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-07-20 | — | — | EP | disclosed |
| EP-0020018-B1 | CHROMAN DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1983-06-01 | — | — | EP | disclosed |
| US-4303656-A | ANOREXIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1981-12-01 | — | — | US | disclosed |
| EP-0020018-A1 | Chroman derivatives, processes for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1980-12-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10766882-B2 | 1,2-naphthoquinone based derivative and method of preparing the same | CYP2S1, GYS2, SLC5A1 | ALDH1A1 688/4885CA12 4298/4885CA1 3086/4885 |
| US-20190076529-A1 | PROSTAGLANDIN COMPOSITIONS AND METHODS FOR THE TREATMENT OF VASOSPASM | PTGIS, PTGIR, PGF | ALDH1A1 2025/4885CA12 3395/4885CA1 2360/4885 |
| US-11246932-B2 | Prostaglandin compositions and methods for the treatment of vasospasm | PTGIS, PTGIR, PGF | ALDH1A1 2025/4885CA12 3395/4885CA1 2360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.