Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | FLT3 | P36888 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 5/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827084 | 0.85 | PDE2A (0.58) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL19709261 | 0.85 | PDE2A (0.58) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL2703655 | 0.85 | PDE2A (0.58) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL10039780 | 0.75 | PDE2A (0.55) | GAALMNA | |
| SCHEMBL13753384 | 0.75 | DRD2 (0.68) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL29949076 | 0.75 | DRD2 (0.68) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL10039649 | 0.74 | PYGL (0.53) | GAALMNAFLT3PYGL | |
| SCHEMBL22809795 | 0.74 | KDM4E (0.58) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL10039653 | 0.73 | DRD2 (0.58) | KDM4EALDH1A1GAAMAPK1DRD2 | |
| SCHEMBL29580477 | 0.73 | KDM4E (1.00) | KDM4EALDH1A1GAAMAPK1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10775375-B2 | Methods for identifying modulators of calcium-sensing receptors | MARS, INCORPORATED (US) | 2020-09-15 | — | — | US | disclosed |
| US-20190324031-A1 | METHODS FOR IDENTIFYING MODULATORS OF CALCIUM-SENSING RECEPTORS | MARS, INCORPORATED (US) | 2019-10-24 | — | — | US | disclosed |
| US-10393740-B2 | Methods for identifying modulators of calcium-sensing receptors | MARS, INCORPORATED (US) | 2019-08-27 | — | — | US | disclosed |
| US-20170356907-A1 | METHODS FOR IDENTIFYING MODULATORS OF CALCIUM-SENSING RECEPTORS | MARS, INCORPORATED (US) | 2017-12-14 | — | — | US | disclosed |