SCHEMBL19712909

SCHEMBL19712909

O=C(Nc1ccccc1)Oc1ccc2ccccc2c1-c1c(O)ccc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.47
KMT2A Q03164 4/20 0.46
MAPT P10636 3/20 0.46
MEN1 O00255 2/20 0.46
GAA P10253 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KDM4E B2RXH2 2/20 0.44
BLM P54132 1/20 0.44
TRPV1 Q8NER1 1/20 0.43
NCEH1 Q6PIU2 1/20 0.43
FAAH O00519 1/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2C19 P33261 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RAB9A P51151 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19712932 0.85 TRPV1 (0.54) KMT2AMAPTMEN1GAAALDH1A1
SCHEMBL9126452 0.80 GAA (0.50) HSP90AA1KMT2AMAPTMEN1GAA
SCHEMBL19712914 0.79 NCEH1 (0.56) KMT2AMAPTMEN1NCEH1FAAH
SCHEMBL16236576 0.79 KMT2A (0.54) KMT2AMAPTMEN1GAAALDH1A1
SCHEMBL15247643 0.79 PIM1 (0.54) KMT2AMAPTMEN1GAAHTT
SCHEMBL9230576 0.78 ALDH1A1 (0.66) HSP90AA1KMT2AMAPTMEN1GAA
SCHEMBL7095605 0.77 HSP90AA1 (0.54) HSP90AA1KMT2AMAPTGAAALDH1A1
SCHEMBL5099061 0.76 MAPT (0.46) KMT2AMAPTMEN1GAAALDH1A1
SCHEMBL417088 0.75 MAPT (0.48) KMT2AMAPTMEN1NCEH1
SCHEMBL16237183 0.75 LMNA (0.66) KMT2AMAPTMEN1SMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10241402-B2 Naphthyl acrylates as writing monomers for photopolymers COVESTRO DEUTSCHLAND AG (DE) 2019-03-26 US disclosed
US-20170363957-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170363957-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS NEFM, ACR, DIAPH1 HSP90AA1 1554/4885KMT2A 1291/4885MAPT 207/4885
US-10241402-B2 Naphthyl acrylates as writing monomers for photopolymers NEFM, ACR, DIAPH1 HSP90AA1 1554/4885KMT2A 1291/4885MAPT 207/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.