SCHEMBL19712948

SCHEMBL19712948

C=C(CCNC(=O)Oc1ccc2ccc(OC)cc2c1-c1c(OC(=O)NCCC(=C)C(=O)O)ccc2ccc(OC)cc12)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 11/20 0.46
MTNR1B P49286 9/20 0.45
HTR2C P28335 1/20 0.41
HTR2B P41595 1/20 0.41
FAAH O00519 1/20 0.41
NQO2 P16083 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17825873 0.83 NCEH1 (0.49) FAAH
SCHEMBL19712927 0.82 MTNR1A (0.48) MTNR1AMTNR1BHTR2CHTR2B
SCHEMBL19712951 0.78 MTNR1A (0.45) MTNR1AMTNR1BHTR2CHTR2B
SCHEMBL20483985 0.72 NCEH1 (0.44)
SCHEMBL2317239 0.71 LMNA (0.40)
SCHEMBL2316314 0.70 TAAR1 (0.49) FAAH
SCHEMBL2314524 0.70 MGLL (0.56)
SCHEMBL2315627 0.70 TAAR1 (0.43) FAAH
SCHEMBL2314389 0.69 KDM4E (0.46)
SCHEMBL2319261 0.69 NPC1 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10241402-B2 Naphthyl acrylates as writing monomers for photopolymers COVESTRO DEUTSCHLAND AG (DE) 2019-03-26 US disclosed
US-20170363957-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS COVESTRO DEUTSCHLAND AG (DE) 2017-12-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170363957-A1 NAPHTHYL ACRYLATES AS WRITING MONOMERS FOR PHOTOPOLYMERS NEFM, ACR, DIAPH1 MTNR1A 3557/4885MTNR1B 3748/4885HTR2C 682/4885
US-10241402-B2 Naphthyl acrylates as writing monomers for photopolymers NEFM, ACR, DIAPH1 MTNR1A 3557/4885MTNR1B 3748/4885HTR2C 682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.