Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | CBX7 | O95931 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.55 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.55 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.53 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19714625 | 0.89 | TP53 (0.62) | TP53MAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL19714580 | 0.87 | MAPT (0.64) | USP2MAPTPIN1TSHRRAB9A | |
| SCHEMBL19714443 | 0.83 | LMNA (0.60) | USP2TP53MAPTRXFP1TSHR | |
| SCHEMBL19714466 | 0.81 | KMT2A (0.65) | USP2TP53MAPTTSHRRAB9A | |
| SCHEMBL19714641 | 0.80 | ALDH1A1 (0.63) | USP2MAPTTSHRRAB9ARECQL | |
| SCHEMBL17824313 | 0.80 | MMP2 (0.54) | USP2MAPTTSHRRAB9ASMN1; SMN2 | |
| SCHEMBL19714594 | 0.79 | KMT2A (0.53) | USP2MAPTTSHRRAB9ARECQL | |
| SCHEMBL31134125 | 0.78 | PIN1 (0.68) | USP2HSD17B10TP53MAPTPIN1 | |
| SCHEMBL19714285 | 0.78 | POLB (0.59) | HSD17B10TP53MAPTTSHRRAB9A | |
| SCHEMBL17824291 | 0.78 | LMNA (0.50) | USP2MAPTTSHRRAB9ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362184-A1 | PRO-SURVIVAL COMPOUNDS | HERIOT-WATT UNIVERSITY (GB) | 2017-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362184-A1 | PRO-SURVIVAL COMPOUNDS | MCL1, MKI67, MORF4L1 | USP2 2298/4885HSD17B10 2109/4885TP53 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.