SCHEMBL19718041

SCHEMBL19718041

CO[C@]1(C)CCC23C[C@H]1C(C)(C)C2CC[C@H]3C

nearest known ligand 0.65

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ ALOX15 P16050 2/20 0.65
▸ ALDH1A1 P00352 1/20 0.62
▸ LMNA P02545 1/20 0.62
▸ THRB P10828 1/20 0.62
▸ MAPK1 P28482 1/20 0.62
▸ CYP17A1 P05093 3/20 0.49
▸ CYP19A1 P11511 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL873204 1.00 ALOX15 (0.65) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL32678404 1.00 ALOX15 (0.65) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL14841540 1.00 ALOX15 (0.65) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL8738678 1.00 ALOX15 (0.65) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL19718040 1.00 ALOX15 (0.65) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL18138230 1.00 ALOX15 (0.65) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL24534431 1.00 ALOX15 (0.65) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL17836881 1.00 ALOX15 (0.65) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL1773862 1.00 ALOX15 (0.65) ALOX15ALDH1A1LMNATHRBMAPK1
SCHEMBL3502857 1.00 ALOX15 (0.65) ALOX15ALDH1A1LMNATHRBMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3672692-B1 BLENDS CONTAINING ENANTIOMERICALLY PURE AMBROCENIDE® SYMRISE AG (DE) 2023-08-16 — — EP claimed
US-11091723-B2 Use of ambrocenide® for intensifying a lily of the valley scent SYMRISE AG (DE) 2021-08-17 — — US claimed
US-11066625-B2 Blends containing enantiomerically pure Ambrocenide® SYMRISE AG (DE) 2021-07-20 — — US claimed
US-20200239810-A1 USE OF AMBROCENIDE ® FOR INTENSIFYING A LILY OF THE VALLEY SCENT SYMRISE AG (DE) 2020-07-30 — — US claimed
US-20200172830-A1 BLENDS CONTAINING ENANTIOMERICALLY PURE AMBROCENIDE® SYMRISE AG (DE) 2020-06-04 — — US claimed
EP-2947078-B1 Novel mixtures with (4aR, 5R, 7aS, 9R) -octahydro-2,2,5,8,8,9a-hexamethyl-4h-4a, 9-methanoazuleno (5,6-d) -1,3-dioxol) (ambrocenide ®) SYMRISE AG (DE) 2018-03-21 — — EP claimed
US-12529008-B2 Natural semi-solid perfume EXPRESSIONS PARFUMEES (FR) 2026-01-20 — — US disclosed
EP-3749281-B1 PERFUMING COMPLEX AND COMPOSITION OF PERFUMED WATER EXPRESSIONS PARFUMEES (FR) 2024-06-26 — — EP disclosed
US-11965144-B2 Perfume complex and perfumed water composition EXPRESSIONS PARFUMÉES (FR) 2024-04-23 — — US disclosed
WO-2023170261-A1 READY-FOR-USE MILKY, VISCOUS AND STICKY PERFUME COMPLEX AND ASSOCIATED PERFUMED COMPOSITION EXPRESSIONS PARFUMEES (FR) 2023-09-14 — — WO disclosed
EP-3672692-B1 BLENDS CONTAINING ENANTIOMERICALLY PURE AMBROCENIDE® SYMRISE AG (DE) 2023-08-16 — — EP disclosed
WO-2023067179-A1 FRAGRANCING COMPLEX, FRAGRANCING COMPOSITION AND FRAGRANCED AQUEOUS COMPOSITION OF NATURAL ORIGIN EXPRESSIONS PARFUMEES (FR) 2023-04-27 — — WO disclosed
US-20230043162-A1 NATURAL SEMI-SOLID PERFUME EXPRESSIONS PARFUMEES (FR) 2023-02-09 — — US disclosed
US-20210230502-A1 PERFUME COMPLEX AND PERFUMED WATER COMPOSITION EXPRESSIONS PARFUMÉES (FR) 2021-07-29 — — US disclosed
US-11066625-B2 Blends containing enantiomerically pure Ambrocenide® SYMRISE AG (DE) 2021-07-20 — — US disclosed
WO-2021123110-A1 SEMI-SOLID NATURAL PERFUME EXPRESSIONS PARFUMEES (FR) 2021-06-24 — — WO disclosed
EP-3749281-A1 PERFUME COMPLEX AND SCENTED WATER COMPOSITION Expressions Parfumees (FR) 2020-12-16 — — EP disclosed
WO-2019154892-A1 PERFUME COMPLEX AND SCENTED WATER COMPOSITION EXPRESSIONS PARFUMÉES (FR) 2019-08-15 — — WO disclosed
EP-3471691-A1 MIXTURE COMPRISING AT LEAST DIHYDRO-5-PENTYL-2(3H)-FURANONE AND 2,4-DIMETHYL-4-PHENYLTETRAHYDROFURAN AND USE THEREOF FOR MASKING UNPLEASANT ODOURS Expressions Parfumees (FR) 2019-04-24 — — EP disclosed
WO-2017216478-A1 MIXTURE COMPRISING AT LEAST DIHYDRO-5-PENTYL-2(3H)-FURANONE AND 2,4-DIMETHYL-4-PHENYLTETRAHYDROFURAN AND USE THEREOF FOR MASKING UNPLEASANT ODOURS EXPRESSIONS PARFUMEES (FR) 2017-12-21 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172830-A1 BLENDS CONTAINING ENANTIOMERICALLY PURE AMBROCENIDE® OR51E2, CYP1B1, QDPR ALOX15 465/4885ALDH1A1 431/4885LMNA 3423/4885
US-20230043162-A1 NATURAL SEMI-SOLID PERFUME TES, DSG1, CUTA ALOX15 576/4885ALDH1A1 2665/4885LMNA 4636/4885
US-20200239810-A1 USE OF AMBROCENIDE ® FOR INTENSIFYING A LILY OF THE VALLEY SCENT OR51E2, OR10J3, ALG3 ALOX15 710/4885ALDH1A1 1767/4885LMNA 3395/4885
US-11091723-B2 Use of ambrocenide® for intensifying a lily of the valley scent OR51E2, OR10J3, TRPA1 ALOX15 585/4885ALDH1A1 1494/4885LMNA 3625/4885
US-11066625-B2 Blends containing enantiomerically pure Ambrocenide® OR51E2, CYP1B1, QDPR ALOX15 465/4885ALDH1A1 431/4885LMNA 3423/4885
US-12529008-B2 Natural semi-solid perfume TES, TAS2R50, TAS2R10 ALOX15 879/4885ALDH1A1 1674/4885LMNA 4729/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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