Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.72 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.65 |
| ▸ | HTR6 | P50406 | 3/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 8/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.53 |
| ▸ | NQO2 | P16083 | 1/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12352575 | 0.85 | MTNR1A (0.69) | MTNR1AHTR6AKR1C3AKR1C2MTNR1B | |
| SCHEMBL30485879 | 0.85 | MTNR1A (0.80) | MTNR1AHTR6 | |
| SCHEMBL24877705 | 0.85 | MTNR1A (0.80) | MTNR1AHTR6 | |
| SCHEMBL3224617 | 0.84 | MTNR1A (0.76) | MTNR1AAKR1C3MTNR1BNQO2KDM4E | |
| SCHEMBL5616413 | 0.84 | MTNR1A (1.00) | MTNR1AHTR6AKR1C3AKR1C2MTNR1B | |
| SCHEMBL4341029 | 0.82 | HTR6 (0.51) | MTNR1AADRB2HTR6NPSR1HSD17B10 | |
| Oxalic Acid SCHEMBL7438526 | 0.82 | HTR6 (0.73) | MTNR1AADRB2HTR6AKR1C3AKR1C2 | |
| SCHEMBL29194213 | 0.81 | ADRB2 (0.72) | MTNR1AADRB2HTR6MTNR1BNQO2 | |
| SCHEMBL28924882 | 0.80 | ALOX5 (0.59) | MTNR1AADRB2HTR6AKR1C3AKR1C2 | |
| Oxalic Acid SCHEMBL27614859 | 0.80 | ADRB2 (0.62) | MTNR1AADRB2HTR6AKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106359566-B | A kind of composite preservative of berry and preparation method thereof and application method | 南京农业大学 | 2019-11-08 | — | — | CN | claimed |
| CN-109566374-A | A kind of high yield pea seedlings and its implantation methods | 李靖 | 2019-04-05 | — | — | CN | claimed |
| CN-109329048-A | A kind of test tube seedling of roxburgh anoectochilus terminal bud germplasm grows store method slowly | 谭兴江 | 2019-02-15 | — | — | CN | claimed |
| CN-109220794-A | A kind of ultralow temperature detoxification store method of water chestnut germplasm | 尹纪岩 | 2019-01-18 | — | — | CN | claimed |
| CN-109053535-A | A kind of preparation method of n-acetyl-5-methoxytryptamine | 罗田县新普生药业有限公司 | 2018-12-21 | — | — | CN | claimed |
| CN-106359566-A | Berry composite preservative and preparation method and application method thereof | 南京农业大学 | 2017-02-01 | — | — | CN | claimed |
| EP-1476152-A4 | USE OF MELATONIN ANALOGUES FOR INDUCTION OF GENERAL ANESTHESIA | UNIV IOWA RES FOUND (US) | 2007-04-11 | — | — | EP | claimed |
| EP-1476152-A2 | USE OF MELATONIN ANALOGUES FOR INDUCTION OF GENERAL ANESTHESIA | University of Iowa Research Foundation (US) | 2004-11-17 | — | — | EP | claimed |
| WO-2003070177-A2 | USE OF MELATONIN ANALOGUES FOR INDUCTION OF GENERAL ANESTHESIA | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2003-08-28 | — | — | WO | claimed |
| EP-1326601-A2 | THE USE OF MELATONIN FOR INDUCTION OF GENERAL ANESTHESIA | University of Iowa Research Foundation (US) | 2003-07-16 | — | — | EP | claimed |
| US-20020120002-A1 | Use of melatonin analogues for induction of general anesthesia | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2002-08-29 | — | — | US | claimed |
| WO-2002024181-A2 | THE USE OF MELATONIN FOR INDUCTION OF GENERAL ANESTHESIA | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2002-03-28 | — | — | WO | claimed |
| WO-1994024865-A1 | METHODS FOR CONTROLLING FLOWERING IN PLANTS | THE REGENTS OF THE UNIVERSTIY OF CALIFORNIA (US) | 1994-11-10 | — | — | WO | claimed |
| JP-10101644-A | — | — | None | — | — | JP | disclosed |
| JP-3145419-A | — | — | None | — | — | JP | disclosed |
| EP-4366722-A1 | MELAFENOXATE AND DERIVATIVES THEREOF FOR USE IN TREATING CIRCADIAN RHYTHM SLEEP DISORDERS WITH OR WITHOUT NEURODEGENERATIVE DISEASES | NLS Pharmaceutics AG (CH) | 2024-05-15 | — | — | EP | disclosed |
| EP-0514373-A1 | Use of melatonin for treating pre-menstrual syndrome. | AMR INT (US) | 1992-11-25 | — | — | EP | disclosed |
| WO-1991012007-A1 | METHOD OF TREATING PRE-MENSTRUAL SYNDROME | APPLIED MED RES (US) | 1991-08-22 | — | — | WO | disclosed |
| JP-H03145419-A | DRUG OF PREVENTING ULTRAVIOLET LIGHT AGING | SHISEIDO CO LTD | 1991-06-20 | — | — | JP | disclosed |
| US-4411881-A | Composition and method for stabilizing radiolabeled compounds using thiocarbonylated diethylenetriamines | NEW ENGLAND NUCLEAR CORPORATION (US) | 1983-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020120002-A1 | Use of melatonin analogues for induction of general anesthesia | MTNR1A, MTNR1B, AANAT | MTNR1A 1/4885ADRB2 26/4885HTR6 12/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.