Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.84 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.84 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.84 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.84 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.84 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.84 |
| ▸ | TRPM8 | Q7Z2W7 | 8/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11460179 | 0.92 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL11460180 | 0.92 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL11434928 | 0.92 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL17340454 | 0.92 | GABRA1 (1.00) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL17340500 | 0.88 | GABRA1 (0.93) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL17340474 | 0.87 | GABRA1 (0.91) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL17340468 | 0.87 | GABRA1 (0.91) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL10270783 | 0.87 | TRPM8 (1.00) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL28408661 | 0.87 | TRPM8 (1.00) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL10270781 | 0.85 | TRPM8 (1.00) | GABRA1GABRG2GABRB3GABRA3GABRA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10350192-B2 | Lactate dehydrogenase inhibitor and antiepileptic drug containing the same | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2019-07-16 | — | — | US | disclosed |
| US-20180015068-A1 | LACTATE DEHYDROGENASE INHIBITOR AND ANTIEPILEPTIC DRUG CONTAINING THE SAME | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2018-01-18 | — | — | US | disclosed |
| EP-3257510-A1 | LACTATE DEHYDROGENASE INHIBITOR AND ANTIEPILEPTIC DRUG CONTAINING SAME | National University Corporation Okayama University (JP) | 2017-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180015068-A1 | LACTATE DEHYDROGENASE INHIBITOR AND ANTIEPILEPTIC DRUG CONTAINING THE SAME | LDHA, LDHB, ALDH5A1 | GABRA1 706/4885GABRG2 795/4885GABRB3 467/4885 |
| US-10350192-B2 | Lactate dehydrogenase inhibitor and antiepileptic drug containing the same | LDHA, LDHB, ALDH5A1 | GABRA1 706/4885GABRG2 795/4885GABRB3 467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.