SCHEMBL19721986

SCHEMBL19721986

C=C(CO)C(=O)Oc1ccc(-c2ccc(C3CCC(CCCCC)CC3)cc2)c(C)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.37
ALDH1A1 P00352 1/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 1/20 0.36
DGAT1 O75907 4/20 0.35
SOAT1 P35610 1/20 0.35
RARB P10826 2/20 0.34
RAB9A P51151 1/20 0.34
FFAR4 Q5NUL3 1/20 0.33
EPHX1 P07099 1/20 0.33
MCHR1 Q99705 1/20 0.33
MMP2 P08253 2/20 0.32
MMP3 P08254 2/20 0.32
MEN1 O00255 1/20 0.32
MAPK1 P28482 1/20 0.32
KMT2A Q03164 1/20 0.32
ESR2 Q92731 1/20 0.32
PTPN11 Q06124 1/20 0.31
P2RY14 Q15391 1/20 0.31
MMP1 P03956 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19755071 0.99 CYP2C9 (0.36) CYP2C9ALDH1A1LMNAMAPTDGAT1
SCHEMBL19721925 0.92 MMP2 (0.35) CYP2C9ALDH1A1LMNAMAPTDGAT1
SCHEMBL19721898 0.91 CYP2C9 (0.37) CYP2C9ALDH1A1LMNAMAPTDGAT1
SCHEMBL19722139 0.90 CYP2C9 (0.36) CYP2C9ALDH1A1LMNAMAPTDGAT1
SCHEMBL19721879 0.89 DGAT1 (0.35) CYP2C9ALDH1A1LMNAMAPTDGAT1
SCHEMBL19721876 0.89 DGAT1 (0.36) CYP2C9ALDH1A1LMNAMAPTDGAT1
SCHEMBL19721990 0.89 CYP2C9 (0.42) CYP2C9ALDH1A1LMNAMAPTDGAT1
SCHEMBL19854423 0.89 CYP2C9 (0.37) CYP2C9ALDH1A1LMNAMAPTDGAT1
SCHEMBL20313609 0.89 CYP2C9 (0.37) CYP2C9ALDH1A1LMNAMAPTDGAT1
SCHEMBL19722321 0.88 RAB9A (0.37) CYP2C9ALDH1A1LMNAMAPTRARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 US disclosed
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 EP disclosed
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element JNC CORPORATION (JP) 2019-08-27 US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 WO disclosed
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORPORATION (JP) 2017-12-28 US disclosed
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element SP1, HVCN1, CXCR1 CYP2C9 4226/4885ALDH1A1 3882/4885LMNA 1014/4885
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SP1, SPIN1, SAV1 CYP2C9 4442/4885ALDH1A1 3267/4885LMNA 1269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.