SCHEMBL19721876

SCHEMBL19721876

C=C(CO)C(=O)Oc1ccc(-c2ccc(C3CCC(CCF)CC3)cc2)c(C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 4/20 0.36
SOAT1 P35610 1/20 0.36
FFAR4 Q5NUL3 2/20 0.35
CYP2C9 P11712 2/20 0.34
EPHX1 P07099 1/20 0.34
CYP3A4 P08684 1/20 0.34
ESR2 Q92731 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
OXTR P30559 1/20 0.33
AVPR1A P37288 1/20 0.33
MMP2 P08253 2/20 0.33
MMP3 P08254 2/20 0.33
MMP1 P03956 1/20 0.33
MMP9 P14780 1/20 0.33
MMP14 P50281 1/20 0.33
APP P05067 1/20 0.32
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19721986 0.89 CYP2C9 (0.37) DGAT1SOAT1FFAR4CYP2C9EPHX1
SCHEMBL19755071 0.89 CYP2C9 (0.36) DGAT1SOAT1FFAR4CYP2C9EPHX1
SCHEMBL19721958 0.84 FFAR4 (0.38) DGAT1SOAT1FFAR4CYP2C9CYP3A4
SCHEMBL19722083 0.82 ESR2 (0.36) DGAT1SOAT1FFAR4CYP2C9CYP3A4
SCHEMBL19721887 0.82 MCHR1 (0.39) DGAT1SOAT1FFAR4CYP2C9CYP3A4
SCHEMBL19721925 0.81 MMP2 (0.35) DGAT1SOAT1FFAR4CYP2C9ALDH1A1
SCHEMBL22596497 0.80 FFAR4 (0.39) DGAT1SOAT1FFAR4EPHX1NR1H4
SCHEMBL19721898 0.80 CYP2C9 (0.37) DGAT1SOAT1FFAR4CYP2C9CYP3A4
SCHEMBL19721879 0.79 DGAT1 (0.35) DGAT1SOAT1FFAR4CYP2C9EPHX1
SCHEMBL19722139 0.79 CYP2C9 (0.36) DGAT1SOAT1FFAR4CYP2C9ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210214615-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY UNIT JNC CORPORATION (JP) 2021-07-15 US disclosed
EP-3257839-B1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2019-09-04 EP disclosed
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element JNC CORPORATION (JP) 2019-08-27 US disclosed
WO-2018025974-A1 LIQUID-CRYSTAL DISPLAY ELEMENT AND DISPLAY DEVICE JNC株式会社 2018-02-08 WO disclosed
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORPORATION (JP) 2017-12-28 US disclosed
EP-3257839-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2017-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10392339-B2 Polymerizable polar compound, liquid crystal composition, and liquid crystal display element SP1, HVCN1, CXCR1 DGAT1 4507/4885SOAT1 2400/4885FFAR4 2665/4885
US-20170369418-A1 POLYMERIZABLE POLAR COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT SP1, SPIN1, SAV1 DGAT1 4598/4885SOAT1 2543/4885FFAR4 2555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.