Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25403099 | 0.89 | ALDH1A1 (0.45) | ALDH1A1PKMVDRDHODHCYP2D6 | |
| SCHEMBL26286109 | 0.85 | CCR5 (0.44) | ALDH1A1PKMVDRDHODHCYP2D6 | |
| SCHEMBL4583291 | 0.83 | PKM (0.42) | ALDH1A1PKMVDRDHODHMAPT | |
| SCHEMBL19725071 | 0.82 | CA2 (0.44) | ALDH1A1PKMMEN1KMT2ACYP1A2 | |
| SCHEMBL9172287 | 0.81 | GLA (0.44) | ALDH1A1GLAVDRDHODHMAPT | |
| SCHEMBL4432214 | 0.81 | CA12 (0.46) | ALDH1A1PKMVDRDHODHCYP2D6 | |
| SCHEMBL3446685 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GLADHODHMAPTTDP1 | |
| SCHEMBL2941143 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GLADHODHMAPTTDP1 | |
| SCHEMBL2938778 | 0.79 | ALDH1A1 (0.46) | ALDH1A1GLADHODHMAPTTDP1 | |
| SCHEMBL1031702 | 0.79 | ALDH1A1 (0.44) | ALDH1A1PKMVDRDHODHSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210205461-A1 | Rapidly Released Bioorthogonal Caging Groups | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2021-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210205461-A1 | Rapidly Released Bioorthogonal Caging Groups | CBR3, CBR1, CNOT9 | ALDH1A1 3686/4885GLA 3943/4885PKM 4810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.