SCHEMBL19730139

SCHEMBL19730139

CC(C)(C)OC(=O)N(C(=O)OC(C)(C)C)c1nc(F)nc2[nH]cnc12

nearest known ligand 0.33

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
POLB P06746 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
PDPK1 O15530 1/20 0.32
USP30 Q70CQ3 1/20 0.32
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
CACNA1G O43497 1/20 0.31
CACNA1B Q00975 1/20 0.31
CACNA1C Q13936 1/20 0.31
XBP1 P17861 1/20 0.31
RECQL P46063 1/20 0.31
SSTR4 P31391 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29593049 1.00 L3MBTL1 (0.33) L3MBTL1TDP1POLBNPSR1PDPK1
SCHEMBL26068373 0.86 MEN1 (0.34) L3MBTL1TDP1POLBNPSR1PDPK1
SCHEMBL19730138 0.86 TDP1 (0.33) L3MBTL1TDP1POLBNPSR1PDPK1
SCHEMBL19730149 0.86 L3MBTL1 (0.36) L3MBTL1TDP1POLBNPSR1PDPK1
SCHEMBL19730137 0.85 L3MBTL1 (0.33) L3MBTL1TDP1POLBNPSR1PDPK1
SCHEMBL13505462 0.80 PDPK1 (0.38) L3MBTL1TDP1POLBNPSR1PDPK1
SCHEMBL29863128 0.80 PDPK1 (0.38) L3MBTL1TDP1POLBNPSR1PDPK1
SCHEMBL19730148 0.80 CACNA1G (0.35) L3MBTL1TDP1POLBNPSR1PDPK1
SCHEMBL30002876 0.77 JAK1 (0.39) PDPK1MEN1KMT2A
SCHEMBL22939319 0.76 SYK (0.39) L3MBTL1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12370208-B2 Adenosine derivative and pharmaceutical composition comprising the same BRII BIOSCIENCES, INC. (US) 2025-07-29 US disclosed
US-20230226093-A1 ADENOSINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME BRII BIOSCIENCES, INC. 2023-07-20 US disclosed
US-20230226093-A1 ADENOSINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME BRII BIOSCIENCES, INC. 2023-07-20 US disclosed
US-20220288098-A1 ADENOSINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME BRII BIOSCIENCES, INC. 2022-09-15 US disclosed
US-20220048912-A1 CYCLOBUTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS JANSSEN PHARMACEUTICA NV (BE) 2022-02-17 US disclosed
EP-3894394-A1 CYCLOBUTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS Janssen BioPharma, Inc. (US) 2021-10-20 EP disclosed
WO-2020121122-A1 CYCLOBUTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS Janssen Biopharma, Inc. (US) 2020-06-18 WO disclosed
US-20170362235-A1 ADENYLYL CYCLASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND METHOD OF USE THEREOF VASADE BIOSCIENCES, INC. 2017-12-21 US disclosed
US-9650342-B2 Compositions and methods of treating retinal disease ALDEYRA THERAPEUTICS, INC. (US) 2017-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226093-A1 ADENOSINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ADAR, ADA, ADORA2A L3MBTL1 1456/4885TDP1 170/4885POLB 99/4885
US-12370208-B2 Adenosine derivative and pharmaceutical composition comprising the same ADAR, ADA, ADORA2A L3MBTL1 1456/4885TDP1 170/4885POLB 99/4885
US-20170362235-A1 ADENYLYL CYCLASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND METHOD OF USE THEREOF ADCY1, ADCY2, ADCY5 L3MBTL1 2316/4885TDP1 1462/4885POLB 3528/4885
US-20220048912-A1 CYCLOBUTYL NUCLEOSIDE ANALOGS AS ANTI-VIRALS TYMP, POLB, HMBS L3MBTL1 3182/4885TDP1 1216/4885POLB 2/4885
US-20220288098-A1 ADENOSINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME ADAR, ADA, ADORA2A L3MBTL1 1456/4885TDP1 170/4885POLB 99/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.