SCHEMBL19732878

SCHEMBL19732878

CCCCCCCC(CC(=O)O)Sc1ccc(F)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.44
TBXA2R P21731 3/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ATM Q13315 1/20 0.41
S1PR2 O95136 2/20 0.41
S1PR1 P21453 2/20 0.41
MMP2 P08253 2/20 0.39
MMP9 P14780 2/20 0.39
MMP12 P39900 2/20 0.39
HTR7 P34969 1/20 0.39
MAPT P10636 1/20 0.38
GAA P10253 1/20 0.38
S1PR4 O95977 1/20 0.37
S1PR3 Q99500 1/20 0.37
ALOX5 P09917 1/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9109127 0.87 ALOX5 (0.48) GPR84MEN1KMT2AATMS1PR2
SCHEMBL19732884 0.85 PPARG (0.40) MEN1KMT2AATMMMP9HTR7
SCHEMBL7067078 0.84 MMP9 (0.46) GPR84MMP2MMP9ALOX5PPARG
SCHEMBL6935204 0.80 PPARG (0.56) MEN1KMT2AATMALOX5PPARG
SCHEMBL10474456 0.74 HTT (0.55) MEN1KMT2AMAPT
SCHEMBL10474458 0.74 HTT (0.55) MEN1KMT2AMAPT
SCHEMBL6930760 0.74 MMP9 (0.63) MEN1KMT2AATMMMP9GAA
SCHEMBL6928817 0.74 ALOX5 (0.48) MEN1KMT2AATMMMP9ALOX5
SCHEMBL4269734 0.74 PTGS2 (0.42) GPR84MMP2MMP9MMP12PPARG
SCHEMBL24227300 0.73 GPR84 (0.60) GPR84MEN1KMT2AMAPTPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475260-B1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR UNIV KONSTANZ (DE) 2022-03-30 EP disclosed
US-10961196-B2 Compounds for use as an anti-bacterial or anti-fungal agent and as a zinc sensor Universität Konstanz (DE) 2021-03-30 US disclosed
US-10961196-B2 Compounds for use as an anti-bacterial or anti-fungal agent and as a zinc sensor Universität Konstanz (DE) 2021-03-30 US disclosed
US-20190218183-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR Universität Konstanz (DE) 2019-07-18 US disclosed
US-20190218183-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR Universität Konstanz (DE) 2019-07-18 US disclosed
EP-3475260-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR Universität Konstanz (DE) 2019-05-01 EP disclosed
WO-2017220205-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR Universität Konstanz (DE) 2017-12-28 WO disclosed
EP-3260445-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR Universität Konstanz (DE) 2017-12-27 EP disclosed
EP-3260445-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR Universität Konstanz (DE) 2017-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190218183-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR ZFR, ZC3HAV1, ZFX GPR84 1225/4885TBXA2R 4532/4885MEN1 2629/4885
US-10961196-B2 Compounds for use as an anti-bacterial or anti-fungal agent and as a zinc sensor ZFR, ZC3HAV1, ZFX GPR84 1225/4885TBXA2R 4532/4885MEN1 2629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.