SCHEMBL19732884

SCHEMBL19732884

CCCCCCCC(CC(=O)OC)Sc1ccc(F)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARG P37231 3/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
MMP9 P14780 1/20 0.39
MMP13 P45452 1/20 0.39
ADAM17 P78536 1/20 0.39
GAA P10253 3/20 0.39
PKM P14618 1/20 0.38
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ATM Q13315 1/20 0.36
HTR7 P34969 1/20 0.36
ZDHHC7 Q9NXF8 1/20 0.36
PPARA Q07869 2/20 0.36
HPGD P15428 2/20 0.35
HDAC3 O15379 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC2 Q92769 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19732878 0.85 GPR84 (0.44) PPARGMAPTMMP9GAAMEN1
SCHEMBL7067078 0.75 MMP9 (0.46) PPARGMMP9MMP13ADAM17PPARA
SCHEMBL7063846 0.75 MMP1 (0.60) MMP9MMP13ADAM17HDAC3HDAC1
SCHEMBL6935204 0.74 PPARG (0.56) PPARGHTTMEN1KMT2AATM
SCHEMBL6656147 0.74 FAAH (0.41) ALDH1A1MAPTHTTGAAPKM
SCHEMBL6928817 0.74 ALOX5 (0.48) PPARGMMP9MMP13ADAM17MEN1
SCHEMBL6930760 0.74 MMP9 (0.63) PPARGMMP9MMP13ADAM17GAA
SCHEMBL9109127 0.73 ALOX5 (0.48) PPARGALDH1A1MAPTHTTMMP9
SCHEMBL20997245 0.72 MMP1 (0.59) ALDH1A1MAPTHTTMMP9MMP13
SCHEMBL27535885 0.71 MMP9 (0.59) PPARGMMP9MMP13ADAM17GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3475260-B1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR UNIV KONSTANZ (DE) 2022-03-30 EP disclosed
US-10961196-B2 Compounds for use as an anti-bacterial or anti-fungal agent and as a zinc sensor Universität Konstanz (DE) 2021-03-30 US disclosed
US-10961196-B2 Compounds for use as an anti-bacterial or anti-fungal agent and as a zinc sensor Universität Konstanz (DE) 2021-03-30 US disclosed
US-20190218183-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR Universität Konstanz (DE) 2019-07-18 US disclosed
US-20190218183-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR Universität Konstanz (DE) 2019-07-18 US disclosed
EP-3475260-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR Universität Konstanz (DE) 2019-05-01 EP disclosed
WO-2017220205-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR Universität Konstanz (DE) 2017-12-28 WO disclosed
EP-3260445-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR Universität Konstanz (DE) 2017-12-27 EP disclosed
EP-3260445-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR Universität Konstanz (DE) 2017-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190218183-A1 COMPOUNDS FOR USE AS AN ANTI-BACTERIAL OR ANTI-FUNGAL AGENT AND AS A ZINC SENSOR ZFR, ZC3HAV1, ZFX PPARG 2261/4885ALDH1A1 4356/4885MAPT 942/4885
US-10961196-B2 Compounds for use as an anti-bacterial or anti-fungal agent and as a zinc sensor ZFR, ZC3HAV1, ZFX PPARG 2261/4885ALDH1A1 4356/4885MAPT 942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.