SCHEMBL19733159

SCHEMBL19733159

c1ccc(Nc2cc3c4ccccc4[nH]c3c3ccccc23)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 9/20 0.52
MMP13 P45452 9/20 0.52
MMP9 P14780 8/20 0.52
MMP8 P22894 6/20 0.52
MAPT P10636 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MEN1 O00255 1/20 0.48
GLA P06280 1/20 0.48
GAA P10253 1/20 0.48
RECQL P46063 1/20 0.48
KMT2A Q03164 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
KIF11 P52732 4/20 0.47
EGFR P00533 2/20 0.46
JAK2 O60674 1/20 0.43
TP53 P04637 1/20 0.43
HTT P42858 1/20 0.43
KLK7 P49862 1/20 0.43
ELANE P08246 1/20 0.43
GABRP O00591 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30346387 0.84 MAPT (0.59) MMP2MMP13MMP9MMP8MAPT
SCHEMBL8415803 0.84 MAPT (0.59) MMP2MMP13MMP9MMP8MAPT
SCHEMBL19897395 0.78 KDM4E (0.51) MMP2MMP13MMP9MMP8MAPT
SCHEMBL16835578 0.78 PARP14 (0.60) MAPTKDM4EMEN1GLAGAA
SCHEMBL22923206 0.76 MEN1 (0.67) MAPTKDM4EMEN1GLAGAA
Diphenylamine SCHEMBL27846286 0.76 ALDH1A1 (0.67) MMP2MMP13MMP9MMP8MAPT
SCHEMBL23927106 0.75 MMP2 (0.57) MMP2MMP13MMP9MMP8MEN1
SCHEMBL559711 0.74 MMP2 (0.47) MMP2MMP13MMP9MMP8MEN1
SCHEMBL15811038 0.74 MMP2 (0.44) MMP2MMP13MMP9MMP8MAPT
SCHEMBL13563976 0.73 KIF11 (0.78) MAPTKDM4EMEN1GLAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3351523-B1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEMICAL LTD (KR) 2020-11-04 EP claimed
US-10730812-B2 Double spiro compound and organic light-emitting element comprising same LG CHEM, LTD. (KR) 2020-08-04 US claimed
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US claimed
EP-3321246-B1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2020-04-15 EP claimed
US-10421721-B2 Heterocyclic compound and organic light emitting device comprising same LG CHEM, LTD. (KR) 2019-09-24 US claimed
EP-3351531-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2018-07-25 EP claimed
EP-3351523-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG Chem, Ltd. (KR) 2018-07-25 EP claimed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US claimed
EP-3321246-A2 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2018-05-16 EP claimed
US-20180111887-A1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US claimed
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-02-08 US claimed
EP-3378853-B1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2024-04-17 EP disclosed
US-11208368-B2 Double-spiro type compound and organic light-emitting device containing same LG CHEM, LTD. (KR) 2021-12-28 US disclosed
US-10873035-B2 Heterocyclic compound and organic light emitting diode containing same LG CHEM, LTD. 2020-12-22 US disclosed
EP-3351523-B1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEMICAL LTD (KR) 2020-11-04 EP disclosed
EP-3321246-A2 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2018-05-16 EP disclosed
US-20180111887-A1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2018-04-26 US disclosed
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2018-02-08 US disclosed
US-20180002256-A1 DOUBLE-SPIRO TYPE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-01-04 US disclosed
EP-3260438-A1 DOUBLE-SPIRO TYPE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING SAME LG Chem, Ltd. (KR) 2017-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11208368-B2 Double-spiro type compound and organic light-emitting device containing same NR2E3, CRY1, CRY2 MMP2 4749/4885MMP13 4766/4885MMP9 4079/4885
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 MMP2 4877/4885MMP13 4862/4885MMP9 4393/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 MMP2 4877/4885MMP13 4862/4885MMP9 4393/4885
US-10421721-B2 Heterocyclic compound and organic light emitting device comprising same CRY1, CRY2, PER2 MMP2 4885/4885MMP13 4832/4885MMP9 4403/4885
US-20180037547-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME CRY1, CRY2, PER2 MMP2 4885/4885MMP13 4832/4885MMP9 4403/4885
US-20180002256-A1 DOUBLE-SPIRO TYPE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CONTAINING SAME NR2E3, CRY1, CRY2 MMP2 4749/4885MMP13 4766/4885MMP9 4079/4885
US-10730812-B2 Double spiro compound and organic light-emitting element comprising same NR2E3, CRY1, CRY2 MMP2 4849/4885MMP13 4845/4885MMP9 4171/4885
US-10873035-B2 Heterocyclic compound and organic light emitting diode containing same CRY1, CRY2, PER2 MMP2 4885/4885MMP13 4870/4885MMP9 4694/4885
US-20180111887-A1 DOUBLE SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME NR2E3, CRY1, CRY2 MMP2 4849/4885MMP13 4845/4885MMP9 4171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.