Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6448966 | 0.90 | KCNH2 (0.44) | HRH1LMNADRD3KCNH2HTR2A | |
| SCHEMBL11369436 | 0.88 | OPRM1 (0.41) | HRH1LMNADRD3KCNH2HTR2A | |
| SCHEMBL1968862 | 0.85 | LMNA (0.64) | HRH1LMNADRD3KCNH2HTR2A | |
| SCHEMBL4579722 | 0.84 | HRH1 (0.53) | HRH1LMNADRD3KCNH2HTR2A | |
| SCHEMBL8680660 | 0.82 | OPRD1 (0.45) | HRH1LMNADRD3KCNH2HTR2A | |
| SCHEMBL2456709 | 0.80 | HRH1 (0.74) | HRH1LMNADRD3KCNH2HTR2A | |
| SCHEMBL6452273 | 0.78 | OPRM1 (0.43) | HRH1LMNADRD3KCNH2HTR2A | |
| SCHEMBL6449196 | 0.78 | OPRM1 (0.43) | HRH1LMNADRD3KCNH2HTR2A | |
| SCHEMBL11369491 | 0.78 | OPRM1 (0.43) | HRH1LMNADRD3KCNH2HTR2A | |
| SCHEMBL1968701 | 0.78 | LMNA (0.57) | HRH1LMNADRD3KCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476445-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110295014-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-12-01 | — | — | US | disclosed |
| US-8022220-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-09-20 | — | — | US | disclosed |
| EP-1958935-B1 | Process for the production of terfenadine and carebastine derivatives with microorganisms | ALBANY MOLECULAR RES INC (US) | 2011-06-22 | — | — | EP | disclosed |
| US-20100137605-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-7691615-B2 | Process for the production of piperidine derivatives with microorganisms | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-04-06 | — | — | US | disclosed |
| US-7678915-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-03-16 | — | — | US | disclosed |
| US-20100010227-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-7560561-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-07-14 | — | — | US | disclosed |
| EP-1339864-B1 | PROCESS FOR THE PRODUCTION OF PIPERIDINE DERIVATIVES WITH MICROORGANISMS | AMR TECHNOLOGY INC (US) | 2008-12-31 | — | — | EP | disclosed |
| US-5663412-A | Aromatic ketones | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-09-02 | — | — | US | disclosed |
| WO-1997023213-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-07-03 | — | — | WO | disclosed |
| US-5589487-A | Piperidine derivatives and process for their production | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-12-31 | — | — | US | disclosed |
| US-5581011-A | Aromatic ketones and processes for their preparation | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-12-03 | — | — | US | disclosed |
| US-5578610-A | Piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0723958-A1 | Synthesis of substantially pure terfenadine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-07-31 | — | — | EP | disclosed |
| EP-0703902-A4 | — | ALBANY MOLECULAR RES INC (US) | 1996-04-10 | — | — | EP | disclosed |
| EP-0703902-A1 | PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | ALBANY MOLECULAR RESEARCH, INC. (US) | 1996-04-03 | — | — | EP | disclosed |
| WO-1995000482-A1 | PIPERIDINE DERIVATIVES AND PROCESS FOR THEIR PRODUCTION | ALBANY MOLECULAR RESEARCH, INC. (US) | 1995-01-05 | — | — | WO | disclosed |
| US-4285957-A | ANTIALLERGENS; ANTIHISTAMINES; BRONCHODILATOR AGENTS | RICHARDSON-MERRELL INC. (US) | 1981-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110295014-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | OR10J3, NR1H2, NR1H3 | HRH1 313/4885LMNA 4284/4885DRD3 448/4885 |
| US-20100137605-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | HPD, PTMA, HAAO | HRH1 727/4885LMNA 2264/4885DRD3 687/4885 |
| US-20100010227-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | DDC, HPD, ALDH7A1 | HRH1 882/4885LMNA 2378/4885DRD3 933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.