Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | IRS1 | P35568 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19744921 | 0.77 | SMN1; SMN2 (0.41) | L3MBTL1ALDH1A1LMNASLC6A3MAPT | |
| SCHEMBL19747206 | 0.73 | ALDH1A1 (0.52) | L3MBTL1ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL11152963 | 0.73 | POLB (0.46) | L3MBTL1ALDH1A1IDO1LMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL11165095 | 0.72 | POLB (0.45) | L3MBTL1ALDH1A1IDO1LMNACYP3A4 | |
| SCHEMBL9334108 | 0.68 | TSHR (0.31) | TSHR | |
| SCHEMBL8995181 | 0.68 | — | — | |
| SCHEMBL11174901 | 0.68 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1IDO1LMNAMAPT | |
| SCHEMBL4302 | 0.67 | POLB (0.44) | L3MBTL1ALDH1A1IDO1CYP3A4CYP2D6 | |
| SCHEMBL192919 | 0.66 | — | — | |
| SCHEMBL6332296 | 0.65 | L3MBTL1 (0.49) | L3MBTL1ALDH1A1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3471729-A1 | THERAPEUTIC COMPOUNDS | Rutgers, the State University of New Jersey (US) | 2019-04-24 | — | — | EP | disclosed |
| WO-2017222930-A1 | THERAPEUTIC COMPOUNDS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2017-12-28 | — | — | WO | disclosed |