SCHEMBL19759490

SCHEMBL19759490

C=CCCCCCCn1c(=O)n(CCCCCCNC(=O)OC2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)c(=O)n(CCCCCCNC(=O)OC2CC(C)(C)N(OCCCCCCCC)C(C)(C)C2)c1=O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.35
ACHE P22303 11/20 0.33
BCHE P06276 3/20 0.33
SGPL1 O95470 1/20 0.33
GAA P10253 1/20 0.32
EPHX1 P07099 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19759491 0.86 EPHX1 (0.39) EPHX2EPHX1
SCHEMBL19422674 0.81 ACHE (0.47) EPHX2ACHEBCHEGAAEPHX1
SCHEMBL17884347 0.77 TSHR (0.40) EPHX2ACHEGAA
SCHEMBL6300796 0.77 DRD2 (0.32) SGPL1GAA
SCHEMBL8944642 0.75 EPHX2 (0.36) EPHX2ACHEGAAEPHX1
SCHEMBL17883538 0.74 EPHX1 (0.45) EPHX2ACHEGAAEPHX1
SCHEMBL185586 0.73 EPHX2 (0.39) EPHX2ACHEEPHX1
SCHEMBL22699687 0.73 EPHX2 (0.39) EPHX2ACHEEPHX1
SCHEMBL28647242 0.73 EPHX2 (0.39) EPHX2ACHEEPHX1
SCHEMBL12047216 0.73 EPHX2 (0.39) EPHX2ACHEEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180002285-A1 STERICALLY HINDERED ALKYL AND OXYALKYL AMINE LIGHT STABILIZERS 3M INNOVATIVE PROPERTIES COMPANY 2018-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180002285-A1 STERICALLY HINDERED ALKYL AND OXYALKYL AMINE LIGHT STABILIZERS AAAS, MAP1LC3A, ACTL6A EPHX2 3108/4885ACHE 3850/4885BCHE 3946/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.