SCHEMBL6300796

SCHEMBL6300796

CC(C)(O)CON1C(C)(C)CC(OC(=O)NCCCCCCn2c(=O)n(CCCCCCNC(=O)OC3CC(C)(C)N(OCC(C)(C)O)C(C)(C)C3)c(=O)n(CCCCCCNC(=O)OC3CC(C)(C)N(OCC(C)(C)O)C(C)(C)C3)c2=O)CC1(C)C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 0.32
GAA P10253 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
MAN2B1 O00754 1/20 0.32
SGPL1 O95470 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6300772 0.90 TDP1 (0.35) GAAMEN1KMT2AMAN2B1SGPL1
SCHEMBL19759490 0.77 EPHX2 (0.35) GAASGPL1
SCHEMBL524344 0.74 NAAA (0.39) GAAMEN1KMT2A
SCHEMBL21582136 0.74 NAAA (0.39) GAAMEN1KMT2A
SCHEMBL3957275 0.73 EPHX2 (0.39) GAAMEN1KMT2A
SCHEMBL12227670 0.73 TSHR (0.47) GAAMEN1KMT2A
SCHEMBL38998 0.72 KMT2A (0.38) GAAMEN1KMT2A
SCHEMBL39302 0.72 KMT2A (0.38) GAAMEN1KMT2A
SCHEMBL9400326 0.72 TSHR (0.50) GAAMEN1KMT2ASGPL1
SCHEMBL6300794 0.72 MEN1 (0.30) GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6586507-B2 For stabilizing polyolefins, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation, also for stabilizing acid catalyzed and ambient cured coatings systems CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-01 US claimed
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2003-06-26 US claimed
US-6392041-B1 OXIDATION, HEAT AND RADIATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION 2002-05-21 US claimed
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2002-05-16 US claimed
US-6872832-B2 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-03-29 US disclosed
EP-1363883-A1 HYDROXY-SUBSTITUTED N-ALKOXY HINDERED AMINES AND COMPOSITIONS STABILIZED THEREWITH Ciba SC Holding AG (CH) 2003-11-26 EP disclosed
US-6586507-B2 For stabilizing polyolefins, especially thermoplastic polyolefins, against the deleterious effects of oxidative, thermal and actinic radiation, also for stabilizing acid catalyzed and ambient cured coatings systems CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-01 US disclosed
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2003-06-26 US disclosed
WO-2002070481-A1 HYDROXY-SUBSTITUTED N-ALKOXY HINDERED AMINES AND COMPOSITIONS STABILIZED THEREWITH CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-09-12 WO disclosed
US-6392041-B1 OXIDATION, HEAT AND RADIATION RESISTANCE CIBA SPECIALTY CHEMICALS CORPORATION 2002-05-21 US disclosed
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2002-05-16 US disclosed
US-6376584-B1 OXIDATION RESISTANCE, HEAT RESISTANCE, PHOTOSTABILITY CIBA SPECIALTY CHEMICALS CORPORATION 2002-04-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, HAO2, POLH DRD2 861/4885GAA 1255/4885MEN1 2374/4885
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, POLH, OGFOD1 DRD2 592/4885GAA 1590/4885MEN1 2478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.