SCHEMBL19770489

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21252586	0.93	ALOX5 (0.43)	ALOX5SOS1PRKDCCYP1A2CYP1A1
	SCHEMBL19770480	0.93	ALOX5 (0.45)	ALOX5PRKDCCYP1A2CYP1A1CYP1B1
	SCHEMBL25624636	0.89	ALOX5 (0.42)	ALOX5PRKDCCYP1A2ALDH1A1HPGD
	SCHEMBL20109974	0.89	SOS1 (0.42)	SOS1PRKDCCYP1A2CYP1A1CYP1B1
	SCHEMBL27046691	0.88	CYP1A2 (0.40)	ALOX5SOS1PRKDCCYP1A2CYP1A1
	SCHEMBL23426675	0.88	ALOX5 (0.39)	ALOX5SOS1PRKDCCYP1A2CYP1A1
	SCHEMBL22708021	0.88	ALOX5 (0.42)	ALOX5SOS1PRKDCCYP1A2CYP1A1
	SCHEMBL22546990	0.88	ESR1 (0.41)	ALOX5SOS1PRKDCCYP1A2CYP1A1
	SCHEMBL23426499	0.88	ALOX5 (0.39)	ALOX5SOS1PRKDCCYP1A2CYP1A1
	SCHEMBL18842430	0.87	CYP1A1 (0.42)	PRKDCCYP1A2CYP1A1CYP1B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.