SCHEMBL1977481

SCHEMBL1977481

COc1cc(CO[PH](=O)OCc2cc(OC)cc(OC)c2)cc(OC)c1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
CYP19A1 P11511 1/20 0.44
CALM1 P0DP23 3/20 0.40
POLB P06746 1/20 0.39
KMT2A Q03164 1/20 0.39
ABCB1 P08183 2/20 0.38
AKR1B1 P15121 1/20 0.38
DAO P14920 1/20 0.38
PTGS2 P35354 1/20 0.37
TSHR P16473 1/20 0.37
CYP1A1 P04798 1/20 0.37
CYP1B1 Q16678 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PTPN1 P18031 1/20 0.37
NOS2 P35228 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28961391 0.89 CALM1 (0.53) ALDH1A1CALM1KMT2AAKR1B1PTGS2
SCHEMBL1977482 0.84 ALDH1A1 (0.42) ALDH1A1CYP19A1CALM1POLBKMT2A
SCHEMBL28917697 0.82 TP53 (0.39) ALDH1A1CYP19A1
SCHEMBL7189496 0.81 IDO1 (0.61) ABCB1
Butane SCHEMBL16290769 0.80 PTGS2 (0.42) ALDH1A1CYP19A1CALM1POLBKMT2A
SCHEMBL7197241 0.79 IDO1 (0.55) ALDH1A1CALM1POLBTSHR
SCHEMBL23580820 0.78 EGLN1 (0.31) CYP19A1ABCB1
SCHEMBL28961393 0.76 CALM1 (0.51) ALDH1A1CALM1KMT2AAKR1B1PTGS2
SCHEMBL31052 0.75 ALDH1A1 (0.58) ALDH1A1CYP19A1CALM1ABCB1AKR1B1
SCHEMBL7889540 0.75 ALDH1A1 (0.58) ALDH1A1CYP19A1CALM1ABCB1AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105686-A1 A PROCESS FOR THE SYNTHESIS OF STILBENE AND INTERMEDIATES THEREOF FERTIS INDIA PVT LTD (IN) 2024-05-23 WO claimed
WO-2024105686-A1 A PROCESS FOR THE SYNTHESIS OF STILBENE AND INTERMEDIATES THEREOF FERTIS INDIA PVT LTD (IN) 2024-05-23 WO disclosed
CN-102001949-B 3,5-dimethoxystilbene derivative, preparation method and application thereof in anti-drug resistant bacteria UNIV SOUTH CHINA TECH 2014-07-02 CN disclosed
US-8524782-B2 Key intermediate for the preparation of Stilbenes, solid forms of Pterostilbene, and methods for making the same LAURUS LABS PRIVATE LIMITED (IN) 2013-09-03 US disclosed
US-20110144212-A1 KEY INTERMEDIATE FOR THE PREPARATION OF STILBENES, SOLID FORMS OF PTEROSTILBENE, AND METHODS FOR MAKING THE SAME APTUIT LAURUS PRIVATE LIMITED (IN) 2011-06-16 US disclosed
CN-102001949-A 3,5-dimethoxystilbene derivative, preparation method and application thereof in anti-drug resistant bacteria UNIV SOUTH CHINA TECH 2011-04-06 CN disclosed
WO-2010010578-A2 A KEY INTERMEDIATE FOR THE PREPARATION OF STILBENES APTUIT LAURUS PRIVATE LIMITED (IN) 2010-01-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144212-A1 KEY INTERMEDIATE FOR THE PREPARATION OF STILBENES, SOLID FORMS OF PTEROSTILBENE, AND METHODS FOR MAKING THE SAME SIRT5, SQLE, PDHB ALDH1A1 1220/4885CYP19A1 898/4885CALM1 4576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.