SCHEMBL1977482

SCHEMBL1977482

COc1cc(CO[PH](=O)O)cc(OC)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
CYP19A1 P11511 1/20 0.42
CALM1 P0DP23 2/20 0.41
KMT2A Q03164 3/20 0.41
POLB P06746 1/20 0.41
AKR1B1 P15121 1/20 0.40
PTGS2 P35354 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
PTPN1 P18031 1/20 0.38
NOS2 P35228 1/20 0.38
ENPP2 Q13822 1/20 0.38
HIF1A Q16665 1/20 0.38
CYP3A4 P08684 1/20 0.38
GABRA1 P14867 1/20 0.38
GABRG2 P18507 1/20 0.38
GABRB3 P28472 1/20 0.38
GABRA3 P34903 1/20 0.38
GABRA2 P47869 1/20 0.38
GABRB2 P47870 1/20 0.38
MEN1 O00255 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL16290769 0.95 PTGS2 (0.42) ALDH1A1CYP19A1CALM1KMT2APOLB
SCHEMBL28961393 0.91 CALM1 (0.51) ALDH1A1CALM1KMT2AAKR1B1PTGS2
SCHEMBL9017643 0.88 FFAR4 (0.42) CYP19A1CALM1PTGS2PTPN1NOS2
SCHEMBL1977481 0.84 ALDH1A1 (0.46) ALDH1A1CYP19A1CALM1KMT2APOLB
SCHEMBL28917699 0.84 TP53 (0.38) ALDH1A1CYP19A1
SCHEMBL8507775 0.82 IDO1 (0.57)
SCHEMBL8507266 0.81 IDO1 (0.52) ALDH1A1CALM1POLBCYP3A4
SCHEMBL23580823 0.80 EGLN1 (0.32) ENPP2
Butane SCHEMBL5292210 0.79 IDO1 (0.53)
SCHEMBL5661795 0.78 MET (0.48) ALDH1A1AKR1B1PTPN1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105686-A1 A PROCESS FOR THE SYNTHESIS OF STILBENE AND INTERMEDIATES THEREOF FERTIS INDIA PVT LTD (IN) 2024-05-23 WO claimed
WO-2024105686-A1 A PROCESS FOR THE SYNTHESIS OF STILBENE AND INTERMEDIATES THEREOF FERTIS INDIA PVT LTD (IN) 2024-05-23 WO disclosed
CN-102001949-B 3,5-dimethoxystilbene derivative, preparation method and application thereof in anti-drug resistant bacteria UNIV SOUTH CHINA TECH 2014-07-02 CN disclosed
US-8524782-B2 Key intermediate for the preparation of Stilbenes, solid forms of Pterostilbene, and methods for making the same LAURUS LABS PRIVATE LIMITED (IN) 2013-09-03 US disclosed
US-20110144212-A1 KEY INTERMEDIATE FOR THE PREPARATION OF STILBENES, SOLID FORMS OF PTEROSTILBENE, AND METHODS FOR MAKING THE SAME APTUIT LAURUS PRIVATE LIMITED (IN) 2011-06-16 US disclosed
CN-102001949-A 3,5-dimethoxystilbene derivative, preparation method and application thereof in anti-drug resistant bacteria UNIV SOUTH CHINA TECH 2011-04-06 CN disclosed
WO-2010010578-A2 A KEY INTERMEDIATE FOR THE PREPARATION OF STILBENES APTUIT LAURUS PRIVATE LIMITED (IN) 2010-01-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110144212-A1 KEY INTERMEDIATE FOR THE PREPARATION OF STILBENES, SOLID FORMS OF PTEROSTILBENE, AND METHODS FOR MAKING THE SAME SIRT5, SQLE, PDHB ALDH1A1 1220/4885CYP19A1 898/4885CALM1 4576/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.