Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13824719 | 0.93 | — | — | |
| Fluoride Ion SCHEMBL11602272 | 0.91 | ACHE (0.41) | ACHENFE2L2TAAR1ESR2CES2 | |
| SCHEMBL9343117 | 0.86 | — | — | |
| Fluorobenzene SCHEMBL28245217 | 0.80 | NFE2L2 (0.33) | ACHENFE2L2 | |
| SCHEMBL1504016 | 0.77 | TSHR (0.37) | TAAR1ESR2MGLLCYP3A4NPC1 | |
| SCHEMBL15404103 | 0.77 | FAAH (0.33) | FAAHMGLL | |
| SCHEMBL8849632 | 0.77 | ACHE (0.44) | ACHEMGLLCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4345410 | 0.77 | ALDH1A1 (0.37) | TAAR1MGLLCYP1A2MAPK1NPC1 | |
| SCHEMBL31619881 | 0.77 | FAAH (0.33) | FAAHMGLL | |
| SCHEMBL27747554 | 0.75 | ALDH1A1 (0.35) | TAAR1MGLLCYP1A2MAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611816-A | Method for efficiently preparing 5-aryl (hetero) ring modified uracil derivative | 中国科学院化学研究所 | 2023-01-17 | — | — | CN | disclosed |
| CN-112876416-B | Diaryl formyl substituted pyrazole compound and preparation method thereof | 浙大城市学院 | 2022-03-29 | — | — | CN | disclosed |
| CN-112876416-A | Diaryl formyl substituted pyrazole compound and preparation method thereof | 浙大城市学院 | 2021-06-01 | — | — | CN | disclosed |
| US-20200031731-A1 | Gold-Catalyzed C-C Cross-Coupling of Boron- and Silicon-Containing Aryl Compounds and Aryldiazonium Compounds by Visible-Light | Universität Heidelberg (DE) | 2020-01-30 | — | — | US | disclosed |
| EP-3555029-A1 | GOLD-CATALYZED C-C CROSS-COUPLING OF BORON- AND SILICON-CONTAINING ARYL COMPOUNDS AND ARYLDIAZONIUM COMPOUNDS BY VISIBLE-LIGHT | Universität Heidelberg (DE) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018114914-A1 | GOLD-CATALYZED C-C CROSS-COUPLING OF BORON- AND SILICON-CONTAINING ARYL COMPOUNDS AND ARYLDIAZONIUM COMPOUNDS BY VISIBLE-LIGHT | Universität Heidelberg (DE) | 2018-06-28 | — | — | WO | disclosed |
| EP-3336075-A1 | GOLD-CATALYZED C-C CROSS-COUPLING OF BORON- AND SILICON-CONTAINING ARYL COMPOUNDS AND ARYLDIAZONIUM COMPOUNDS BY VISIBLE-LIGHT | Universität Heidelberg (DE) | 2018-06-20 | — | — | EP | disclosed |
| CN-106431824-A | Industrial production method of 3,3'-difluorobiphenyl | 浙江九洲药业股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| US-20150191493-A1 | NEW PROCESS FOR PREPARING ARYLBORANES BY ARYLATION OF ORGANOBORON COMPOUNDS | Universite de Bordeaux (FR) | 2015-07-09 | — | — | US | disclosed |
| EP-2684887-B1 | New process for preparing arylboranes by arylation of organoboron compounds | UNIV BORDEAUX (FR) | 2015-06-17 | — | — | EP | disclosed |
| EP-2872519-A1 | NEW PROCESS FOR PREPARING ARYLBORANES BY ARYLATION OF ORGANOBORON COMPOUNDS | UNIVERSITE DE BORDEAUX (FR) | 2015-05-20 | — | — | EP | disclosed |
| WO-2014009169-A1 | NEW PROCESS FOR PREPARING ARYLBORANES BY ARYLATION OF ORGANOBORON COMPOUNDS | UNIVERSITE DE BORDEAUX 1 (FR) | 2014-01-16 | — | — | WO | disclosed |
| EP-2684887-A1 | New process for preparing arylboranes by arylation of organoboron compounds | UNIVERSITE DE BORDEAUX I (FR) | 2014-01-15 | — | — | EP | disclosed |
| WO-2012150280-A2 | PREPARATION OF 4,4-DIALKOXY-1-BUTEN-1-YLARENES | LONZA LTD (CH) | 2012-11-08 | — | — | WO | disclosed |
| WO-2012150281-A1 | PREPARATION OF 3,3-DIALKXOY-1-METHYLENEPROPYL ARENES | LONZA LTD (CH) | 2012-11-08 | — | — | WO | disclosed |
| WO-2011072064-A1 | S PIRO [CHROMAN - 4, 4 ' - IMIDAZOL] ONES AS BETA - SECRETASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2011-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200031731-A1 | Gold-Catalyzed C-C Cross-Coupling of Boron- and Silicon-Containing Aryl Compounds and Aryldiazonium Compounds by Visible-Light | HCCS, AHR, CTRC | ACHE 2400/4885NFE2L2 1992/4885TAAR1 1248/4885 |
| US-20150191493-A1 | NEW PROCESS FOR PREPARING ARYLBORANES BY ARYLATION OF ORGANOBORON COMPOUNDS | NISCH, BRD7, BRSK2 | ACHE 3213/4885NFE2L2 2179/4885TAAR1 498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.