Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | PRKCQ | Q04759 | 6/20 | 0.32 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.31 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19769046 | 0.86 | CTSK (0.38) | CTSKSMN1; SMN2ENPP1PRKCQPRKCD | |
| SCHEMBL19880529 | 0.76 | ALDH1A1 (0.38) | CTSKSMN1; SMN2ENPP1PRKCQPRKCD | |
| SCHEMBL19781763 | 0.75 | SMN1; SMN2 (0.40) | CTSKSMN1; SMN2ENPP1PRKCQPRKCD | |
| SCHEMBL22096880 | 0.73 | SMN1; SMN2 (0.35) | CTSKSMN1; SMN2ENPP1PRKCQPRKCD | |
| SCHEMBL21883550 | 0.72 | KDM4E (0.32) | KDM4EALDH1A1GAA | |
| SCHEMBL20621262 | 0.68 | RIPK1 (0.34) | CTSKGAA | |
| SCHEMBL29980078 | 0.67 | ENPP1 (0.40) | CTSKSMN1; SMN2ENPP1FGFR4KDM4E | |
| SCHEMBL19630056 | 0.67 | ENPP1 (0.40) | CTSKSMN1; SMN2ENPP1FGFR4KDM4E | |
| SCHEMBL19779566 | 0.64 | CDK5 (0.38) | CTSKKDM4EALDH1A1NPC1CDK5 | |
| SCHEMBL21883761 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180016252-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2018-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180016252-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR2, SSTR4 | CTSK 617/4885SMN1; SMN2 1197/4885ENPP1 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.