Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 8/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19880529 | 0.81 | ALDH1A1 (0.38) | SMN1; SMN2ENPP1PRKCQPRKCDALDH1A1 | |
| SCHEMBL19781763 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2ENPP1PRKCQPRKCDALDH1A1 | |
| SCHEMBL19769046 | 0.78 | CTSK (0.38) | SMN1; SMN2ENPP1PRKCQPRKCDALDH1A1 | |
| SCHEMBL19779871 | 0.73 | CTSK (0.34) | SMN1; SMN2ENPP1PRKCQPRKCDALDH1A1 | |
| SCHEMBL19630056 | 0.69 | ENPP1 (0.40) | SMN1; SMN2ENPP1ALDH1A1KDM4EGAA | |
| SCHEMBL22096893 | 0.69 | EGLN2 (0.41) | SMN1; SMN2ALDH1A1KDM4EHPGDCTSK | |
| SCHEMBL29980078 | 0.69 | ENPP1 (0.40) | SMN1; SMN2ENPP1ALDH1A1KDM4EGAA | |
| SCHEMBL22096833 | 0.65 | CYP11B1 (0.32) | ALDH1A1KDM4EHTT | |
| SCHEMBL22096851 | 0.65 | CA2 (0.39) | SMN1; SMN2ALDH1A1KDM4EGAAHPGD | |
| SCHEMBL4579364 | 0.65 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10875839-B2 | Somatostatin modulators and uses thereof | Crinetics Pharmaceuticals, Inc. (US) | 2020-12-29 | — | — | US | disclosed |
| US-20200190053-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | Crinetics Pharmaceuticals, Inc. | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190053-A1 | SOMATOSTATIN MODULATORS AND USES THEREOF | SSTR5, SSTR2, SSTR4 | SMN1; SMN2 1197/4885ENPP1 573/4885PRKCQ 1065/4885 |
| US-10875839-B2 | Somatostatin modulators and uses thereof | SSTR5, SSTR2, SSTR4 | SMN1; SMN2 1197/4885ENPP1 573/4885PRKCQ 1065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.