SCHEMBL1978101

SCHEMBL1978101

Fc1cc(F)c(-c2cnc3ncnn3c2)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
PDE10A Q9Y233 1/20 0.33
KIT P10721 2/20 0.32
EGLN2 Q96KS0 1/20 0.32
JAK2 O60674 1/20 0.32
MAP4K4 O95819 1/20 0.32
GRM5 P41594 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11470678 0.77 KDR (0.49) MAPK1KDM4EALDH1A1KITEGLN2
SCHEMBL16996752 0.71 MAPK1 (0.37) MAPK1KDM4EALDH1A1
SCHEMBL24155881 0.68 GRM5 (0.41) GRM5
SCHEMBL23143459 0.68 KDR (0.54) PDE10AMAP4K4
SCHEMBL9903515 0.67 GRM5 (0.43) GRM5
SCHEMBL164144 0.67 KDM4E (0.50) MAPK1KDM4EALDH1A1PDE10A
SCHEMBL1352730 0.66 KDM4E (0.34) MAPK1KDM4EALDH1A1
SCHEMBL4157774 0.66 ALDH1A1 (0.51) MAPK1KDM4EALDH1A1EGLN2
SCHEMBL11485785 0.66 SMN1; SMN2 (0.55) EGLN2MAP4K4
SCHEMBL3471316 0.65 HSD17B10 (0.38) MAPK1KDM4EALDH1A1GRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014079813-A1 PESTICIDAL MIXTURES BASF SE (DE) 2014-05-30 WO claimed
WO-2014079766-A1 PESTICIDAL MIXTURES BASF SE (DE) 2014-05-30 WO claimed
US-12624333-B2 Stable inoculant compositions and methods for producing same NOVOZYMES BIOAG A/S (DK) 2026-05-12 US disclosed
US-11623927-B2 Substituted [1,2,4]triazolo[1,5-a]pyrimidines for stabilizing microtubules THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2023-04-11 US disclosed
EP-4096400-A1 LIQUID SULFONYLUREA COMPOSITIONS FMC Agricultural Caribe Industries Ltd. (BM) 2022-12-07 EP disclosed
CN-114867350-A Low volatility polyamine salts of anionic pesticides 巴斯夫公司 2022-08-05 CN disclosed
US-10080365-B2 Use of strobilurin type compounds for combating phytopathogenic fungi resistant to Qo inhibitors BASF SE (DE) 2018-09-25 US disclosed
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2016-09-01 US disclosed
EP-2997026-A1 SUBSTITUTED ISOXAZOLE DERIVATIVES BASF SE (DE) 2016-03-23 EP disclosed
US-9253980-B2 Use of substituted dithiine-tetracarboximides for combating phytopathogenic fungi BASF SE (DE) 2016-02-09 US disclosed
EP-2943486-A1 SUBSTITUTED [1,2,4]TRIAZOLE AND IMIDAZOLE COMPOUNDS BASF SE (DE) 2015-11-18 EP disclosed
WO-2010072634-A2 POST-HARVEST TREATMENT METHOD BASF SE (DE) 2010-07-01 WO disclosed
EP-2197278-A1 CO-CRYSTALS OF PYRIMETHANIL AND DITHIANON BASF SE (DE) 2010-06-23 EP disclosed
US-20090233795-A1 Fungicidal Mixtres Based On 3-Monosubstituted N-Bipenyl-Pyrazolecarboxamides BASF AKITENGESELLSCHAFT (DE) 2009-09-17 US disclosed
WO-2009047043-A1 CO-CRYSTALS OF PYRIMETHANIL AND DITHIANON BASF SE (DE) 2009-04-16 WO disclosed
US-20090042725-A1 Fungicidal Mixtures Based on 3,5-Disubstituted N-Biphenyl-Pyrazolcarboxamides BASF AKTIENGESELLSCHAFT (DE) 2009-02-12 US disclosed
EP-1942730-A1 SOLID CROP PROTECTION AGENTS CONTAINING POLYALKOXYLATE, METHOD FOR THEIR PRODUCTION AND USE THEREOF BASF SE (DE) 2008-07-16 EP disclosed
EP-1889028-A1 METHOD FOR DETERMINING PESTICIDE RESIDUES IN SOIL OR PLANT MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2008-02-20 EP disclosed
WO-2007048851-A1 SOLID CROP PROTECTION AGENTS CONTAINING POLYALKOXYLATE, METHOD FOR THEIR PRODUCTION AND USE THEREOF BASF SE (DE) 2007-05-03 WO disclosed
WO-2006125644-A1 METHOD FOR DETERMINING PESTICIDE RESIDUES IN SOIL OR PLANT MATERIAL BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10080365-B2 Use of strobilurin type compounds for combating phytopathogenic fungi resistant to Qo inhibitors SQOR, COX5B, UQCRB MAPK1 1771/4885KDM4E 3206/4885ALDH1A1 2278/4885
US-20090042725-A1 Fungicidal Mixtures Based on 3,5-Disubstituted N-Biphenyl-Pyrazolcarboxamides CBR3, CBR1, STS MAPK1 3928/4885KDM4E 3964/4885ALDH1A1 433/4885
US-11623927-B2 Substituted [1,2,4]triazolo[1,5-a]pyrimidines for stabilizing microtubules TUBB1, TUBA1B, TUBA1C MAPK1 729/4885KDM4E 3333/4885ALDH1A1 3710/4885
US-12624333-B2 Stable inoculant compositions and methods for producing same UGDH, MGAM, SORD MAPK1 3337/4885KDM4E 3295/4885ALDH1A1 179/4885
US-20090233795-A1 Fungicidal Mixtres Based On 3-Monosubstituted N-Bipenyl-Pyrazolecarboxamides CBR3, CBR1, CYCS MAPK1 3748/4885KDM4E 3173/4885ALDH1A1 2391/4885
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB MAPK1 1771/4885KDM4E 3206/4885ALDH1A1 2278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.