SCHEMBL1978137

SCHEMBL1978137

Cn1c(CO)cnc1[N+](=O)[O-]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
KDM4E B2RXH2 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.50
ENO1 P06733 1/20 0.49
LMNA P02545 4/20 0.41
THRB P10828 2/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 3/20 0.40
CYP2C19 P33261 3/20 0.38
RECQL P46063 1/20 0.38
PARP1 P09874 1/20 0.38
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
MAPT P10636 1/20 0.37
MEN1 O00255 2/20 0.36
ATM Q13315 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28706167 0.98 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2KDM4EL3MBTL1ENO1
SCHEMBL30893638 0.88 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2KDM4EL3MBTL1ENO1
SCHEMBL30893637 0.86 ENO1 (0.47) ALDH1A1SMN1; SMN2KDM4EL3MBTL1ENO1
SCHEMBL30893639 0.86 ENO1 (0.47) ALDH1A1SMN1; SMN2KDM4EL3MBTL1ENO1
SCHEMBL5709535 0.86 ENO1 (0.47) ALDH1A1SMN1; SMN2KDM4EL3MBTL1ENO1
SCHEMBL12207994 0.84 ENO1 (0.50) ALDH1A1SMN1; SMN2KDM4EL3MBTL1ENO1
SCHEMBL868257 0.82 ENO1 (0.56) ALDH1A1SMN1; SMN2KDM4EL3MBTL1ENO1
SCHEMBL27002702 0.82 ENO1 (0.49) ALDH1A1SMN1; SMN2KDM4EL3MBTL1ENO1
SCHEMBL10917702 0.82 ENO1 (0.49) ALDH1A1SMN1; SMN2KDM4EL3MBTL1ENO1
SCHEMBL12597725 0.81 SMN1; SMN2 (0.42) ALDH1A1SMN1; SMN2KDM4EL3MBTL1ENO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4086242-B1 5-[(2,4-DINITROPHENOXY)METHYL]-1-METHYL-2-NITRO-L H-IMIDAZOLE AND ITS PHARMACEUTICAL USE RIVUS PHARMACEUTICALS INC (US) 2026-04-08 EP claimed
CN-121570433-A Glutamine metabolism regulation nano drug delivery system for enhancing pancreatic cancer targeting and penetration, and preparation method and application thereof 复旦大学 2026-02-27 CN claimed
US-20240425462-A1 Preparation Process of 1-N-Methyl-2-Nitro-5-Hydroxymethyl Imidazole ASCENTAWITS PHARMACEUTICALS, LTD. (CN) 2024-12-26 US claimed
CN-116803989-A Preparation process of 1-N-methyl-2-nitro-5-hydroxymethyl imidazole 深圳艾欣达伟医药科技有限公司 2023-09-26 CN claimed
CN-116583303-B Tripterine conjugates and uses thereof 瑞阳公司 2026-05-12 CN disclosed
EP-4086242-B1 5-[(2,4-DINITROPHENOXY)METHYL]-1-METHYL-2-NITRO-L H-IMIDAZOLE AND ITS PHARMACEUTICAL USE RIVUS PHARMACEUTICALS INC (US) 2026-04-08 EP disclosed
CN-121570433-A Glutamine metabolism regulation nano drug delivery system for enhancing pancreatic cancer targeting and penetration, and preparation method and application thereof 复旦大学 2026-02-27 CN disclosed
EP-4654966-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF OBESITY AND DISEASES ASSOCIATED WITH FAT CELL ENLARGEMENT MELLICELL, INC. (US) 2025-12-03 EP disclosed
US-20250214944-A1 Novel Phenyl Derivatives Rivus Pharmaceuticals, Inc. 2025-07-03 US disclosed
WO-2025056913-A1 COMPOUND AND METHOD OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2025-03-20 WO disclosed
US-20250011348-A1 Synthesis Process of X-IPM, Stable Crystal Form and Application Thereof ASCENTAWITS PHARMACEUTICALS, LTD. (CN) 2025-01-09 US disclosed
US-20240425462-A1 Preparation Process of 1-N-Methyl-2-Nitro-5-Hydroxymethyl Imidazole ASCENTAWITS PHARMACEUTICALS, LTD. (CN) 2024-12-26 US disclosed
EP-1173414-A1 N-PROTECTED AMINES AND THEIR USE AS PRODRUGS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 2002-01-23 EP disclosed
WO-2000064864-A9 N-PROTECTED AMINES AND THEIR USE AS PRODRUGS CANCER RES CAMPAIGN TECH (GB) 2001-12-27 WO disclosed
WO-2000064864-A1 N-PROTECTED AMINES AND THEIR USE AS PRODRUGS CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) 2000-11-02 WO disclosed
EP-0081719-B1 2-NITRO-IMIDAZOLS F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1986-04-23 EP disclosed
US-4515790-A Antiprotozoal 2-nitroimidazole compounds HOFFMANN-LA ROCHE INC. (US) 1985-05-07 US disclosed
EP-0081719-A2 2-Nitro-imidazols F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1983-06-22 EP disclosed
US-3987053-A ANTIMICROBIAL GRUPPO LEPETIT S.P.A. (IT) 1976-10-19 US disclosed
US-3954789-A 2-Nitroimidazole derivatives GRUPPO LEPETIT S.P.A. (IT) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011348-A1 Synthesis Process of X-IPM, Stable Crystal Form and Application Thereof CHRM2, CHRM1, INMT ALDH1A1 4493/4885SMN1; SMN2 4169/4885KDM4E 546/4885
US-20240425462-A1 Preparation Process of 1-N-Methyl-2-Nitro-5-Hydroxymethyl Imidazole DNMT1, COX4I1, NDC1 ALDH1A1 788/4885SMN1; SMN2 895/4885KDM4E 612/4885
US-20250214944-A1 Novel Phenyl Derivatives TFAM, GOT2, NDUFAB1 ALDH1A1 1313/4885SMN1; SMN2 1309/4885KDM4E 615/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.