Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19781784 | 0.79 | TRPA1 (0.34) | KDM4ERAB9AALDH1A1NPC1TGFBR1 | |
| SCHEMBL1913167 | 0.77 | TGFBR1 (0.44) | KDM4ERAB9APOLBNPSR1ALDH1A1 | |
| SCHEMBL20985980 | 0.77 | TGFBR1 (0.34) | KDM4ERAB9AALDH1A1NPC1TGFBR1 | |
| SCHEMBL24460464 | 0.73 | PIK3CA (0.39) | KDM4ERAB9AALDH1A1HPGDNPC1 | |
| SCHEMBL20049572 | 0.72 | NPC1 (0.33) | RAB9APRMT5WDR77NPC1TGFBR1 | |
| SCHEMBL20049571 | 0.72 | PRMT5 (0.32) | PRMT5WDR77TGFBR1 | |
| SCHEMBL22072385 | 0.72 | GABRA1 (0.37) | KDM4ERAB9ANPSR1ALDH1A1NPC1 | |
| SCHEMBL24460481 | 0.71 | POLB (0.39) | KDM4ERAB9APOLBNPSR1TDP1 | |
| SCHEMBL1913154 | 0.68 | KEAP1 (0.38) | HPGDCYP1A2HSD17B10 | |
| SCHEMBL16386458 | 0.67 | TGFBR1 (0.38) | KDM4ETGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013430-A2 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ARENAVIRUS INFECTION | ARISAN THERAPEUTICS INC. (US) | 2018-01-18 | — | — | WO | disclosed |