Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.53 |
| ▸ | GABRP | O00591 | 1/20 | 0.53 |
| ▸ | GABRD | O14764 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.53 |
| ▸ | GABRE | P78334 | 1/20 | 0.53 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.53 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.53 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.53 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29563968 | 0.85 | NPC1 (0.43) | P4HTMGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2900764 | 0.83 | GABRP (0.56) | P4HTMGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4432631 | 0.76 | ALDH1A1 (0.65) | P4HTMGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7993593 | 0.75 | PIK3CD (0.41) | ALDH1A1TSHRSMN1; SMN2TDP1LMNA | |
| SCHEMBL19782115 | 0.75 | KDM4E (0.34) | P4HTMGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL12303329 | 0.74 | GABRP (0.58) | P4HTMGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1403717 | 0.73 | ALDH1A1 (0.53) | ALDH1A1HSD17B10HPGDTSHRLMNA | |
| SCHEMBL575044 | 0.73 | GABRP (0.61) | P4HTMGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL19781647 | 0.72 | NPC1 (0.48) | ALDH1A1HSD17B10HPGDTDP1LMNA | |
| Hydrochloric Acid SCHEMBL7020108 | 0.72 | GABRP (0.59) | P4HTMGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190152962-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2019-05-23 | — | — | US | disclosed |
| WO-2018011746-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | CADILA HEALTHCARE LIMITED (IN) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190152962-A1 | CYCLOPROPYL DERIVATIVES AS ROR-GAMMA MODULATORS | RORC, RORB, RORA | P4HTM 1238/4885GABRP 378/4885GABRD 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.