Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | RAF1 | P04049 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20944365 | 0.84 | GAA (0.59) | L3MBTL1GAAALDH1A1KDM4EDDR1 | |
| SCHEMBL29537205 | 0.84 | GAA (0.59) | L3MBTL1GAAALDH1A1KDM4EDDR1 | |
| SCHEMBL15993406 | 0.81 | PKM (0.44) | GAAALDH1A1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL25898677 | 0.81 | ALDH1A1 (0.48) | L3MBTL1GAAALDH1A1DDR1MAPT | |
| SCHEMBL20956597 | 0.81 | ALDH1A1 (0.45) | L3MBTL1GAAALDH1A1DDR1CYP1A2 | |
| SCHEMBL27028348 | 0.79 | NOS1 (0.45) | GAAALDH1A1KDM4EMAPTPOLB | |
| SCHEMBL4339936 | 0.79 | MAPT (0.52) | L3MBTL1GAAALDH1A1KDM4EMAPT | |
| SCHEMBL1427075 | 0.78 | L3MBTL1 (0.55) | L3MBTL1GAAALDH1A1MAPTPOLB | |
| SCHEMBL3403936 | 0.78 | KDM4E (0.47) | GAAALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL2643391 | 0.77 | CYP1A2 (0.55) | L3MBTL1GAAALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913734-B2 | Substituted aminothiazoles | BARUCH S. BLUMBERG INSTITUTE | 2021-02-09 | — | — | US | disclosed |
| US-20190241552-A1 | SUBSTITUTED AMINOTHIAZOLES | BARUCH S. BLUMBERG INSTITUTE | 2019-08-08 | — | — | US | disclosed |
| WO-2018013508-A1 | SUBSTITUTED AMINOTHIAZOLES | BARUCH S. BLUMBERG INSTITUTE (US) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913734-B2 | Substituted aminothiazoles | ABAT, AADAT, BCAT1 | L3MBTL1 940/4885GAA 3355/4885ALDH1A1 571/4885 |
| US-20190241552-A1 | SUBSTITUTED AMINOTHIAZOLES | ABAT, AADAT, BCAT1 | L3MBTL1 940/4885GAA 3355/4885ALDH1A1 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.