Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | MAT2A | P31153 | 9/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21422263 | 0.85 | TLR8 (0.37) | TLR8MAT2APTGS2CYP11B2ESR2 | |
| SCHEMBL19783990 | 0.84 | TLR8 (0.44) | TLR8MAT2APTGS2CYP11B2ESR2 | |
| SCHEMBL19783867 | 0.77 | CYP11B2 (0.37) | TLR8MAT2APTGS2CYP11B2ESR2 | |
| SCHEMBL19783855 | 0.76 | ADORA2A (0.40) | TLR8MAT2ACYP11B2ESR2CYP11B1 | |
| SCHEMBL19783288 | 0.76 | TLR8 (0.35) | TLR8MAT2APTGS2CYP11B2ESR2 | |
| SCHEMBL19784123 | 0.75 | TLR8 (0.37) | TLR8MAT2APTGS2CYP11B2ESR2 | |
| SCHEMBL19783856 | 0.75 | ESR2 (0.41) | TLR8MAT2AESR2 | |
| SCHEMBL19784126 | 0.74 | TLR8 (0.39) | TLR8MAT2APTGS2CYP11B2ESR2 | |
| SCHEMBL21422279 | 0.74 | ALDH1A1 (0.39) | TLR8CYP11B2ESR2GRIN1GRIN2B | |
| SCHEMBL19783858 | 0.74 | TLR8 (0.45) | TLR8MAT2APTGS2CYP11B2ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3484877-B1 | BICYCLIC COMPOUNDS AS PEST CONTROLLERS | BAYER CROPSCIENCE AG (DE) | 2020-07-01 | — | — | EP | disclosed |
| US-20190297887-A1 | BICYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-10-03 | — | — | US | disclosed |
| WO-2018011111-A1 | BICYCLIC COMPOUNDS AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190297887-A1 | BICYCLIC COMPOUNDS AS PESTICIDES | DDT, BCHE, ACHE | TLR8 3552/4885MAT2A 3274/4885PTGS2 2595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.