SCHEMBL19832033

SCHEMBL19832033

Brc1ccc(-c2ccc(/C(=C\c3ccc(-c4ccccc4)c4ccccc34)c3ccccc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
MAPK1 P28482 1/20 0.43
GRM2 Q14416 1/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37
EGFR P00533 1/20 0.36
CYP1A1 P04798 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP1B1 Q16678 1/20 0.35
ABCG2 Q9UNQ0 2/20 0.33
MMP9 P14780 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
HDAC6 Q9UBN7 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2499606 0.88 RAB9A (0.38) NPC1RAB9ASMN1; SMN2MMP9CTDSP1
SCHEMBL2499605 0.88 RAB9A (0.38) NPC1RAB9ASMN1; SMN2MMP9CTDSP1
SCHEMBL6761889 0.88 CYP19A1 (0.39) ALDH1A1NPC1RAB9ASMN1; SMN2CYP1A2
SCHEMBL14018430 0.84 L3MBTL1 (0.33) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL19784912 0.80 ALDH1A1 (0.38) ALDH1A1MAPK1GRM2NPC1RAB9A
SCHEMBL14018378 0.79 MAPT (0.34) ALDH1A1MAPK1SMN1; SMN2CYP1A2MMP9
SCHEMBL2510220 0.79 CYP19A1 (0.42) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL28652203 0.79 MAPK1 (0.39) ALDH1A1MAPK1GRM2NPC1RAB9A
SCHEMBL986595 0.79 ALDH1A1 (0.42) ALDH1A1MAPK1GRM2NPC1RAB9A
SCHEMBL28037210 0.76 EPRS1 (0.39) ALDH1A1MAPK1GRM2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018021737-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2018-02-01 WO disclosed