Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 2/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.40 |
| ▸ | PTAFR | P25105 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980365 | 0.90 | TLR7 (0.52) | WNT1DYRK1ATLR7TLR9TLR8 | |
| SCHEMBL1979088 | 0.86 | WNT1 (0.51) | WNT1DYRK1ATLR7TLR9TLR8 | |
| SCHEMBL1983761 | 0.86 | BRAF (0.47) | WNT1DYRK1ATLR7TLR9PTAFR | |
| SCHEMBL12598121 | 0.86 | KDM4E (0.44) | WNT1DYRK1ATLR7TLR9TLR8 | |
| SCHEMBL12598125 | 0.85 | DRD2 (0.48) | WNT1DYRK1ATLR7TLR9TLR8 | |
| SCHEMBL1981803 | 0.85 | MTNR1A (0.45) | TLR7TLR9TLR8PTAFR | |
| SCHEMBL473784 | 0.85 | DYRK1A (0.44) | WNT1DYRK1ACHRM4GSK3B | |
| SCHEMBL1978545 | 0.85 | IGF1R (0.41) | WNT1DYRK1ATLR7 | |
| SCHEMBL1981315 | 0.85 | PTAFR (0.47) | WNT1DYRK1ATLR7TLR9PTAFR | |
| SCHEMBL12597832 | 0.84 | DYRK1A (0.45) | WNT1DYRK1ATLR7TLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011070299-A1 | TRI-SUBSTITUTED 9H-BETA-CARBOLINE (OR 9H-PYRIDO[3,4-B]INDOLE) DERIVATIVES, PREPARATION OF SAME AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2011-06-16 | — | — | WO | disclosed |