Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL6319388 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2176783 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL1204417 | 1.00 | MEN1 (0.67) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2176788 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL9655753 | 0.94 | MEN1 (0.60) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28398822 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL2590832 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL28478211 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL10566608 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR | |
| Water SCHEMBL10896609 | 0.94 | MEN1 (0.75) | MEN1KMT2ACA5ACA5BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630187-A1 | PRODUCTION OF SILVER NANOPARTICLES BY GREEN SYNTHESIS USING HAZELNUT HUSK EXTRACT | Bahçesehir Üniversitesi (TR) | 2025-10-15 | — | — | EP | claimed |
| WO-2024123268-A1 | PRODUCTION OF SILVER NANOPARTICLES BY GREEN SYNTHESIS USING HAZELNUT HUSK EXTRACT | BAHCESEHIR UNIVERSITESI (TR) | 2024-06-13 | — | — | WO | claimed |
| CN-116949551-A | EuInO (EuInO) 3 Solvothermal preparation method and application of crystal | 山东越海通信科技股份有限公司 | 2023-10-27 | — | — | CN | claimed |
| US-20090023173-A1 | Luminescence-based methods and probes for measuring cytochrome P450 activity | PROMEGA CORPORATION (US) | 2009-01-22 | — | — | US | claimed |
| EP-4630187-A1 | PRODUCTION OF SILVER NANOPARTICLES BY GREEN SYNTHESIS USING HAZELNUT HUSK EXTRACT | Bahçesehir Üniversitesi (TR) | 2025-10-15 | — | — | EP | disclosed |
| WO-2025027146-A1 | PHOSPHORS FOR HIGH-POWER APPLICATIONS | SEABOROUGH IP I B.V. (NL) | 2025-02-06 | — | — | WO | disclosed |
| EP-4502107-A1 | PHOSPHORS FOR HIGH-POWER APPLICATIONS | Seaborough IP I B.V. (NL) | 2025-02-05 | — | — | EP | disclosed |
| US-20240350646-A1 | METHODS AND COMPOSITIONS FOR DELIVERY TO AND ACROSS THE BLOOD BRAIN BARRIER | NUTECH VENTURES (US) | 2024-10-24 | — | — | US | disclosed |
| WO-2024123268-A1 | PRODUCTION OF SILVER NANOPARTICLES BY GREEN SYNTHESIS USING HAZELNUT HUSK EXTRACT | BAHCESEHIR UNIVERSITESI (TR) | 2024-06-13 | — | — | WO | disclosed |
| CN-118176165-A | Method for the liquid-liquid extraction of rare earth elements or actinides by synergistic combination of a co-solvent hydrotropic agent and an anionic extractant or chelating extractant | 原子能和替代能源委员会 | 2024-06-11 | — | — | CN | disclosed |
| CN-114976474-B | Rare earth monoatomic material, preparation method thereof and application of rare earth monoatomic material as lithium-sulfur battery diaphragm modified material | 齐鲁工业大学 | 2023-12-26 | — | — | CN | disclosed |
| CN-116949551-A | EuInO (EuInO) 3 Solvothermal preparation method and application of crystal | 山东越海通信科技股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| WO-2011070324-A1 | PARTICLES FOR THE TREATMENT OF CANCER IN COMBINATION WITH RADIOTHERAPY | ISIS INNOVATION LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |
| US-20100009445-A1 | RARE EARTH NANOPARTICLES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2010-01-14 | — | — | US | disclosed |
| US-7550637-B2 | Catalyst and process for selective hydrogenation | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2009-06-23 | — | — | US | disclosed |
| EP-2051930-A1 | RARE EARTH NANOPARTICLES | Mayo Foundation for Medical Education and Research (US) | 2009-04-29 | — | — | EP | disclosed |
| WO-2008022147-A1 | RARE EARTH NANOPARTICLES | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2008-02-21 | — | — | WO | disclosed |
| US-20050288538-A1 | Catalyst and process for selective hydrogenation | LOWE DAVID M | 2005-12-29 | — | — | US | disclosed |
| WO-2005051538-A1 | CATALYST AND PROCESS FOR SELECTIVE HYDROGENATION | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2005-06-09 | — | — | WO | disclosed |
| US-20050113614-A1 | Catalyst and process for selective hydrogenation | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023173-A1 | Luminescence-based methods and probes for measuring cytochrome P450 activity | CYP3A43, CYP3A7, CYP3A5 | MEN1 2891/4885KMT2A 4413/4885CA5A 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.