Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13268427 | 0.90 | KMT2A (0.43) | HTR2CLMNAGAAALDH1A1POLB | |
| SCHEMBL1980327 | 0.89 | HTR2C (0.42) | HTR2CGAAALDH1A1POLBRAB9A | |
| SCHEMBL1979666 | 0.84 | PKM (0.41) | HTR2CLMNAALDH1A1POLBRAB9A | |
| SCHEMBL1983453 | 0.84 | ALDH1A1 (0.42) | HTR2CLMNAALDH1A1RAB9APKM | |
| SCHEMBL1980046 | 0.81 | HTR2C (0.43) | HTR2CLMNAGAAALDH1A1RAB9A | |
| SCHEMBL1980442 | 0.79 | MAPT (0.42) | LMNAGAAALDH1A1RAB9APKM | |
| SCHEMBL1978975 | 0.79 | RAB9A (0.48) | HTR2CGAAALDH1A1RAB9APKM | |
| SCHEMBL1984297 | 0.79 | RAB9A (0.46) | GAAALDH1A1POLBRAB9APKM | |
| SCHEMBL13832525 | 0.76 | KEAP1 (0.56) | KEAP1HTR2CLMNAALDH1A1POLB | |
| SCHEMBL1979857 | 0.75 | KEAP1 (0.55) | KEAP1HTR2CLMNAGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509961-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | Autifony Therapeutics Limited (GB) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011069951-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |