Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1980046 | 0.89 | HTR2C (0.43) | ALDH1A1LMNAHTR2CMEN1KMT2A | |
| SCHEMBL1980442 | 0.85 | MAPT (0.42) | ALDH1A1LMNAMEN1KMT2ARAB9A | |
| SCHEMBL1980368 | 0.84 | KEAP1 (0.48) | ALDH1A1LMNAHTR2CMEN1KMT2A | |
| SCHEMBL1980327 | 0.81 | HTR2C (0.42) | ALDH1A1HTR2CMEN1KMT2ARAB9A | |
| SCHEMBL1979666 | 0.81 | PKM (0.41) | ALDH1A1LMNAHTR2CMEN1KMT2A | |
| SCHEMBL13268427 | 0.81 | KMT2A (0.43) | ALDH1A1LMNAHTR2CMEN1KMT2A | |
| SCHEMBL13832396 | 0.77 | LMNA (0.54) | ALDH1A1LMNAHTR2CMEN1KMT2A | |
| SCHEMBL1978975 | 0.76 | RAB9A (0.48) | ALDH1A1HTR2CMEN1KMT2ARAB9A | |
| SCHEMBL1980785 | 0.76 | ALDH1A1 (0.45) | ALDH1A1LMNAHTR2CMEN1KMT2A | |
| SCHEMBL1984297 | 0.76 | RAB9A (0.46) | ALDH1A1MEN1KMT2ARAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509961-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | Autifony Therapeutics Limited (GB) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011069951-A1 | IMIDAZOLIDINEDIONE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |