SCHEMBL19824318

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19131192	0.94	PLA2G2A (0.34)	ALDH1A1MAPTHPGDSMN1; SMN2L3MBTL1
	SCHEMBL19824317	0.92	PLA2G2A (0.35)	ALDH1A1HPGDTSHRL3MBTL1PLA2G2A
	SCHEMBL19196073	0.92	L3MBTL1 (0.36)	SMN1; SMN2L3MBTL1PLA2G2APLA2G4APLA2G10
	SCHEMBL19131658	0.91	ALDH1A1 (0.35)	ALDH1A1MAPTHPGDHSD17B10KDM4E
	SCHEMBL19132436	0.89	CHRNA1 (0.35)	ALDH1A1MAPTHPGDHSD17B10KDM4E
	SCHEMBL19802570	0.87	KDM4E (0.33)	ALDH1A1MAPTHPGDHSD17B10KDM4E
	SCHEMBL19131191	0.86	ENPP3 (0.34)	ALDH1A1MAPTHPGDHSD17B10KDM4E
	SCHEMBL22243909	0.86	PLA2G2A (0.34)	ALDH1A1MAPTHPGDHSD17B10KDM4E
	SCHEMBL22876458	0.86	PLA2G2A (0.34)	SMN1; SMN2L3MBTL1PLA2G2APLA2G4APLA2G10
	SCHEMBL19132325	0.85	GAA (0.34)	SMN1; SMN2L3MBTL1MEN1KMT2ARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.