SCHEMBL19824410

SCHEMBL19824410

O=c1nc(-c2ccccc2)c2c([nH]1)oc1ccccc12

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.53
▸ HSD17B10 Q99714 3/20 0.53
▸ HPGD P15428 3/20 0.53
▸ ALDH1A1 P00352 2/20 0.53
▸ TSHR P16473 1/20 0.53
▸ MAP4K4 O95819 1/20 0.45
▸ PIM1 P11309 1/20 0.45
▸ CSNK1D P48730 1/20 0.45
▸ CSNK2A1 P68400 1/20 0.45
▸ DYRK1A Q13627 1/20 0.45
▸ PIM3 Q86V86 1/20 0.45
▸ CLK4 Q9HAZ1 1/20 0.45
▸ PDE3B Q13370 1/20 0.44
▸ PDE3A Q14432 1/20 0.44
▸ MEN1 O00255 3/20 0.43
▸ KMT2A Q03164 3/20 0.43
▸ NPSR1 Q6W5P4 2/20 0.43
▸ CASP1 P29466 2/20 0.43
▸ MAPT P10636 2/20 0.42
▸ CSF1R P07333 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12838299 0.79 MAOA (0.41) KDM4EHSD17B10HPGDALDH1A1TSHR
SCHEMBL1520200 0.78 L3MBTL1 (0.40) KDM4EHSD17B10HPGDALDH1A1TSHR
SCHEMBL13102148 0.77 MEN1 (0.60) KDM4EHSD17B10HPGDALDH1A1TSHR
SCHEMBL19679787 0.73 MAP4K4 (0.45) KDM4EHSD17B10HPGDALDH1A1TSHR
SCHEMBL17829223 0.70 KDM4E (0.64) KDM4EHSD17B10HPGDALDH1A1TSHR
SCHEMBL4142958 0.69 KDM4E (1.00) KDM4EHSD17B10HPGDALDH1A1TSHR
SCHEMBL22274043 0.69 MAPT (0.50) KDM4ETSHRMEN1KMT2AMAPT
Lithium SCHEMBL30669498 0.68 KDM4E (0.96) KDM4EHSD17B10HPGDALDH1A1TSHR
SCHEMBL18018247 0.68 HCAR2 (0.45) KDM4EHSD17B10HPGDALDH1A1CASP1
SCHEMBL16902387 0.68 KMT2A (0.43) KDM4EHSD17B10HPGDALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10957865-B2 Organic light emitting compound and organic light emitting diode including the same SFC CO., LTD. (KR) 2021-03-23 — — US disclosed
US-20210057655-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2021-02-25 — — US disclosed
EP-3275970-B1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME SFC CO LTD (KR) 2019-05-22 — — EP disclosed
US-20180040834-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2018-02-08 — — US disclosed
US-20180040834-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME SFC CO., LTD. (KR) 2018-02-08 — — US disclosed
EP-3275970-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME SFC Co., Ltd. (KR) 2018-01-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180040834-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME HARS1, ALDH1A2, ALDH1A1 KDM4E 4276/4885HSD17B10 84/4885HPGD 2065/4885
US-20210057655-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DIODE INCLUDING THE SAME HARS1, ALDH1A2, ALDH1A1 KDM4E 4276/4885HSD17B10 84/4885HPGD 2065/4885
US-10957865-B2 Organic light emitting compound and organic light emitting diode including the same HARS1, ALDH1A2, ALDH1A1 KDM4E 4338/4885HSD17B10 86/4885HPGD 2043/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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