Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1520200 | 0.80 | L3MBTL1 (0.40) | MAOAL3MBTL1TDP1CA12CA1 | |
| SCHEMBL19824410 | 0.79 | KDM4E (0.53) | MAOAL3MBTL1TDP1CA12CA1 | |
| SCHEMBL18018247 | 0.70 | HCAR2 (0.45) | MAOAL3MBTL1TDP1CA12CA9 | |
| SCHEMBL2002523 | 0.69 | KDM4E (0.52) | MAOAL3MBTL1TDP1CA12CA9 | |
| SCHEMBL10614221 | 0.68 | MAOA (0.54) | MAOATDP1KDM5AGAAMGAM | |
| SCHEMBL15024931 | 0.67 | ALDH1A1 (0.44) | MAOAL3MBTL1TDP1ALDH1A1KDM4E | |
| SCHEMBL31606608 | 0.67 | ALDH1A1 (0.44) | MAOAL3MBTL1TDP1ALDH1A1KDM4E | |
| Carsalam SCHEMBL17844931 | 0.67 | CA12 (0.48) | MAOACA12CA1CA9KDM5A | |
| Benzoylenurea SCHEMBL29947820 | 0.67 | ALDH1A1 (0.58) | TDP1CA12CA9ALDH1A1KDM4E | |
| Benzoylenurea SCHEMBL357451 | 0.67 | ALDH1A1 (0.58) | TDP1CA12CA9ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053941-A1 | IDO Inhibitors | NEWLINK GENETICS (US) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053941-A1 | IDO Inhibitors | IDO1, IDO2, INMT | MAOA 16/4885L3MBTL1 1178/4885TDP1 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.