SCHEMBL19828596

SCHEMBL19828596

Cc1cc(Cl)c(C)c(C(O)C(F)(F)F)c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 1/20 0.35
PDK2 Q15119 1/20 0.33
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
HTT P42858 1/20 0.30
GPR35 Q9HC97 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19824105 0.78 RAPGEF4 (0.35) PDE2APDK2HTTGPR35
SCHEMBL7073802 0.76 SELL (0.37) PTGS2
SCHEMBL19832541 0.74 GABRA1 (0.35) PDE2APTGS1PTGS2
SCHEMBL4922287 0.71 PDK2 (0.32) PDE2APDK2
SCHEMBL20285908 0.71 LMNA (0.42) HTT
SCHEMBL19832518 0.70 PDE2A (0.32) PDE2A
SCHEMBL19137705 0.70 PDE2A (0.39) PDE2A
SCHEMBL15792053 0.70 PDE2A (0.40) PDE2A
SCHEMBL14141979 0.69 TDP1 (0.35) PDK2PTGS2HTT
SCHEMBL20906137 0.69 PTGS2 (0.30) PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2934135-B1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-01-31 EP disclosed