Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SELL | P14151 | 1/20 | 0.37 |
| ▸ | SELP | P16109 | 1/20 | 0.37 |
| ▸ | SELE | P16581 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784157 | 0.78 | SELL (0.37) | SELLSELPSELEALDH1A1CA2 | |
| SCHEMBL7070057 | 0.78 | TRPA1 (0.45) | ALDH1A1LMNAGAAMAPT | |
| SCHEMBL19824105 | 0.76 | RAPGEF4 (0.35) | — | |
| SCHEMBL19828596 | 0.76 | PDE2A (0.35) | PTGS2 | |
| SCHEMBL14141979 | 0.75 | TDP1 (0.35) | ALDH1A1POLBSMN1; SMN2KDM4ELMNA | |
| SCHEMBL20906137 | 0.75 | PTGS2 (0.30) | PTGS2 | |
| SCHEMBL7128529 | 0.74 | TRPA1 (0.57) | SELLSELPSELEALDH1A1POLB | |
| SCHEMBL14321440 | 0.73 | ALDH1A1 (0.36) | ALDH1A1CA2POLBTYRSMN1; SMN2 | |
| SCHEMBL9614164 | 0.72 | CA2 (0.44) | SELLSELPSELEALDH1A1CA2 | |
| SCHEMBL19828711 | 0.71 | TP53 (0.40) | SMN1; SMN2KDM4ELMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144524-A1 | With an aromatic derivative carrying at least one hydroxyl functional group, wherein the electron-withdrawing group present on the carbonyl compound is selected from fluoroalkyl derivatives, esters, including orthoesters, and nitriles and | RHODIA CHIMIE, FRANCE | 2003-07-31 | — | — | US | claimed |
| US-6541674-B2 | Electron-withdrawing group present on carbonyl compound is selected from fluoroalkyl derivatives, esters, including orthoesters, and nitrites and condensation is carried out in basic medium | RHODIA CHIMIE (FR) | 2003-04-01 | — | — | US | claimed |
| US-20010004670-A1 | Process for the condensation of a carbonyl compound with an aromatic derivative in a basic medium | RHODIA CHIMIE (FR) | 2001-06-21 | — | — | US | claimed |
| US-20030144524-A1 | With an aromatic derivative carrying at least one hydroxyl functional group, wherein the electron-withdrawing group present on the carbonyl compound is selected from fluoroalkyl derivatives, esters, including orthoesters, and nitriles and | RHODIA CHIMIE, FRANCE | 2003-07-31 | — | — | US | disclosed |
| US-6541674-B2 | Electron-withdrawing group present on carbonyl compound is selected from fluoroalkyl derivatives, esters, including orthoesters, and nitrites and condensation is carried out in basic medium | RHODIA CHIMIE (FR) | 2003-04-01 | — | — | US | disclosed |
| US-20010004670-A1 | Process for the condensation of a carbonyl compound with an aromatic derivative in a basic medium | RHODIA CHIMIE (FR) | 2001-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010004670-A1 | Process for the condensation of a carbonyl compound with an aromatic derivative in a basic medium | NCAPH, ODC1, NCAPD2 | SELL 2802/4885SELP 3393/4885SELE 1227/4885 |
| US-20030144524-A1 | With an aromatic derivative carrying at least one hydroxyl functional group, wherein the electron-withdrawing group present on the carbonyl compound is selected from fluoroalkyl derivatives, esters, including orthoesters, and nitriles and | ECE2, HCN4, ETV6 | SELL 3028/4885SELP 3441/4885SELE 556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.