SCHEMBL19832541

SCHEMBL19832541

Cc1cc(Cl)cc(C(O)C(F)(F)F)c1C

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.35
GABRB1 P18505 1/20 0.35
MGLL Q99685 1/20 0.34
PDE2A O00408 1/20 0.32
SCN4A P35499 2/20 0.31
PTGS2 P35354 2/20 0.31
PTGS1 P23219 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18057575 0.78 MGLL (0.48) MGLLPDE2A
SCHEMBL22197395 0.78 CYP3A4 (0.39) MGLLPDE2A
SCHEMBL24458097 0.76 GABRA1 (0.45) GABRA1GABRB1PDE2ASCN4A
SCHEMBL19828596 0.74 PDE2A (0.35) PDE2APTGS2PTGS1
SCHEMBL5843396 0.74 CRHR1 (0.39)
SCHEMBL14321290 0.73 ALDH1A1 (0.42) GABRA1GABRB1PDE2A
SCHEMBL12407088 0.71 GABRA1 (0.54) GABRA1GABRB1SCN4A
SCHEMBL14321599 0.71 TSHR (0.41) MGLLPDE2A
SCHEMBL19832518 0.70 PDE2A (0.32) PDE2A
SCHEMBL19824105 0.70 RAPGEF4 (0.35) MGLLPDE2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2934142-B1 PESTICIDAL COMPOSITIONS AND PROCESSES RELATED THERETO DOW AGROSCIENCES LLC (US) 2018-01-31 EP disclosed