Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831096 | 0.89 | RORC (0.47) | PPARGKDM4ELMNAMAPTHTT | |
| SCHEMBL19831088 | 0.87 | ENPP2 (0.48) | PPARGMAPTMAT2A | |
| SCHEMBL19831051 | 0.87 | PPARG (0.48) | PPARGKDM4EMAPTSMN1; SMN2MAT2A | |
| SCHEMBL19831033 | 0.81 | MAPK8 (0.45) | PPARGMAT2ASRD5A2 | |
| SCHEMBL19831071 | 0.77 | SRD5A2 (0.41) | PPARGMAPTNPSR1SRD5A2 | |
| SCHEMBL19831041 | 0.74 | MAPK8 (0.52) | PPARGKDM4EMAPTNPSR1 | |
| SCHEMBL19831035 | 0.73 | MAPK8 (0.51) | MAPTSMN1; SMN2MAT2A | |
| SCHEMBL19831223 | 0.73 | RORC (0.41) | PPARG | |
| SCHEMBL19831093 | 0.72 | RORC (0.49) | KDM4ELMNANPSR1MAT2ASRD5A2 | |
| SCHEMBL19831090 | 0.72 | SMN1; SMN2 (0.46) | PPARGSMN1; SMN2MAT2ASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018021762-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 현대약품 주식회사 | 2018-02-01 | — | — | WO | disclosed |