Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.45 |
| ▸ | USP14 | P54578 | 9/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MAT2A | P31153 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19831047 | 0.89 | PPARG (0.53) | PPARGMAPTMAT2AKDM4ELMNA | |
| SCHEMBL19831051 | 0.87 | PPARG (0.48) | PPARGMAPTMAT2AKDM4ESMN1; SMN2 | |
| SCHEMBL19831088 | 0.74 | ENPP2 (0.48) | RORCPPARGENPP2MAPTMAT2A | |
| SCHEMBL19831035 | 0.73 | MAPK8 (0.51) | ENPP2MAPTMAT2ASMN1; SMN2 | |
| SCHEMBL14409138 | 0.70 | RORC (0.58) | RORCUSP14 | |
| SCHEMBL2898983 | 0.70 | PPARG (0.62) | PPARG | |
| SCHEMBL3431813 | 0.70 | PPARG (0.60) | PPARGUSP14 | |
| SCHEMBL29456684 | 0.69 | NOTUM (0.67) | MAPTKDM4ELMNAHTTSMN1; SMN2 | |
| SCHEMBL19831033 | 0.69 | MAPK8 (0.45) | RORCPPARGENPP2USP14MAT2A | |
| SCHEMBL24122521 | 0.68 | MAT2A (0.54) | PPARGMAT2AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018021762-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 현대약품 주식회사 | 2018-02-01 | — | — | WO | disclosed |