SCHEMBL1984164

SCHEMBL1984164

O=C(Oc1ccccc1C(=O)OCc1ccccc1)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.67
TDP1 Q9NUW8 4/20 0.67
SLC6A3 Q01959 2/20 0.67
SLC6A2 P23975 1/20 0.67
ALDH1A1 P00352 6/20 0.61
NPSR1 Q6W5P4 3/20 0.57
L3MBTL1 Q9Y468 3/20 0.57
CYP3A4 P08684 2/20 0.57
CYP2C9 P11712 2/20 0.57
CYP2C19 P33261 2/20 0.57
CYP1A2 P05177 1/20 0.57
LMNA P02545 2/20 0.57
HTT P42858 3/20 0.54
TSHR P16473 1/20 0.52
MAPK1 P28482 1/20 0.52
MAPT P10636 3/20 0.52
HPGD P15428 3/20 0.52
SMN1; SMN2 Q16637 1/20 0.51
POLB P06746 1/20 0.51
MEN1 O00255 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6565957 0.93 LMNA (0.69) KMT2ATDP1SLC6A3SLC6A2ALDH1A1
SCHEMBL5710874 0.87 ALDH1A1 (0.65) KMT2ATDP1SLC6A3SLC6A2ALDH1A1
SCHEMBL1282917 0.87 ALDH1A1 (0.65) KMT2ATDP1SLC6A3SLC6A2ALDH1A1
SCHEMBL24729065 0.86 ALDH1A1 (0.63) KMT2ATDP1SLC6A3SLC6A2ALDH1A1
SCHEMBL5710869 0.86 ALDH1A1 (0.63) KMT2ATDP1SLC6A3SLC6A2ALDH1A1
SCHEMBL6565963 0.85 ESR1 (0.69) KMT2ATDP1SLC6A3SLC6A2ALDH1A1
SCHEMBL8356074 0.85 TDP1 (0.79) KMT2ATDP1SLC6A3SLC6A2ALDH1A1
SCHEMBL2875064 0.84 KDM4E (0.62) KMT2ATDP1SLC6A3SLC6A2ALDH1A1
SCHEMBL9574717 0.84 HTT (0.73) KMT2ATDP1SLC6A3SLC6A2ALDH1A1
SCHEMBL5706020 0.83 SLC6A3 (0.69) KMT2ASLC6A3ALDH1A1CYP2C9CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-215728923-U Light guide plate with good light guide effect 江门市中塑板材有限公司 2022-02-01 CN claimed
CN-114410096-B Cobalt-containing organic montmorillonite modified heat aging resistant flame retardant PC optical film material and preparation method thereof 西南科技大学 2023-09-22 CN disclosed
CN-114410096-A Co-containing organic montmorillonite modified heat-aging-resistant flame-retardant PC optical film material and preparation method thereof 西南科技大学 2022-04-29 CN disclosed
CN-215728923-U Light guide plate with good light guide effect 江门市中塑板材有限公司 2022-02-01 CN disclosed
EP-2337544-A2 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE Living Proof, Inc. (US) 2011-06-29 EP disclosed
US-20090068255-A1 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE LIVING PROOF, INC. 2009-03-12 US disclosed
WO-2008134712-A2 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE LIVING PROOF, INC. (US) 2008-11-06 WO disclosed
WO-2008070368-A2 METHODS AND COMPOSITIONS FOR SKIN CARE LIVING PROOF, INC. (US) 2008-06-12 WO disclosed
US-20050244441-A1 Cosmetic compositions UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. 2005-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090068255-A1 USE OF MATRIX METALLOPROTEINASE INHIBITORS IN SKIN CARE MMP1, MMP9, MMP17 KMT2A 2537/4885TDP1 298/4885SLC6A3 4656/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.