Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19465495 | 0.89 | SMN1; SMN2 (0.61) | TP53KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL21678101 | 0.89 | ALDH1A1 (0.56) | KMT2AALDH1A1MEN1NPC1RAB9A | |
| SCHEMBL21678103 | 0.89 | PLAAT3 (0.58) | KMT2AALDH1A1MEN1MAPTHDAC6 | |
| SCHEMBL19465638 | 0.85 | LMNA (0.61) | TP53KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL19853363 | 0.85 | MAOA (0.57) | KMT2AALDH1A1MEN1MAPTMAPK1 | |
| SCHEMBL3056874 | 0.82 | KMT2A (0.71) | KMT2AALDH1A1MEN1MAPTMITF | |
| SCHEMBL8673184 | 0.81 | ALDH1A1 (0.59) | TP53KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL12181478 | 0.79 | ALDH1A1 (0.54) | KMT2AALDH1A1MEN1MAPTL3MBTL1 | |
| SCHEMBL1867492 | 0.78 | ALDH1A1 (0.61) | KMT2AALDH1A1MEN1MAPTHDAC6 | |
| SCHEMBL957078 | 0.78 | TP53 (0.54) | TP53KMT2AALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180748-B2 | Reagents and methods for esterification | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200032238-A1 | Reagents and Methods for Esterification | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2020-01-30 | — | — | US | disclosed |
| US-10428323-B2 | Reagents and methods for esterification | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2019-10-01 | — | — | US | disclosed |
| US-20180037881-A1 | Reagents and Methods for Esterification | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180748-B2 | Reagents and methods for esterification | VIP, BCR, TMPO | TP53 1964/4885KMT2A 4234/4885ALDH1A1 1235/4885 |
| US-10428323-B2 | Reagents and methods for esterification | VIP, BCR, TMPO | TP53 1886/4885KMT2A 4430/4885ALDH1A1 1103/4885 |
| US-20180037881-A1 | Reagents and Methods for Esterification | VIP, BCR, TMPO | TP53 1886/4885KMT2A 4430/4885ALDH1A1 1103/4885 |
| US-20200032238-A1 | Reagents and Methods for Esterification | VIP, BCR, TMPO | TP53 1964/4885KMT2A 4234/4885ALDH1A1 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.