Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.53 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19853442 | 0.89 | TP53 (0.54) | ALDH1A1RAB9ANPC1KMT2AMEN1 | |
| SCHEMBL21678103 | 0.84 | PLAAT3 (0.58) | ALDH1A1LMNAKMT2AMEN1CYP2C19 | |
| SCHEMBL19465495 | 0.84 | SMN1; SMN2 (0.61) | ALDH1A1RAB9ANPC1LMNAPOLB | |
| SCHEMBL19853363 | 0.84 | MAOA (0.57) | ALDH1A1RAB9ALMNAKMT2AMEN1 | |
| SCHEMBL19465638 | 0.81 | LMNA (0.61) | ALDH1A1RAB9APLA2G1BATG4BNPC1 | |
| SCHEMBL5230740 | 0.80 | HDAC6 (0.72) | ALDH1A1RAB9ANPC1LMNAKMT2A | |
| SCHEMBL21390031 | 0.80 | RAB9A (0.55) | ALDH1A1RAB9APLA2G1BATG4BNPC1 | |
| SCHEMBL20911008 | 0.76 | RAB9A (0.75) | ALDH1A1RAB9APLA2G1BATG4BNPC1 | |
| SCHEMBL18415459 | 0.75 | LMNA (0.66) | ALDH1A1RAB9APLA2G1BATG4BNPC1 | |
| SCHEMBL3056874 | 0.75 | KMT2A (0.71) | ALDH1A1RAB9ANPC1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11180748-B2 | Reagents and methods for esterification | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2021-11-23 | — | — | US | disclosed |
| US-20200032238-A1 | Reagents and Methods for Esterification | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11180748-B2 | Reagents and methods for esterification | VIP, BCR, TMPO | ALDH1A1 1235/4885RAB9A 1621/4885PLA2G1B 3436/4885 |
| US-20200032238-A1 | Reagents and Methods for Esterification | VIP, BCR, TMPO | ALDH1A1 1235/4885RAB9A 1621/4885PLA2G1B 3436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.