SCHEMBL19862482

SCHEMBL19862482

O=C(COS(=O)(=O)C(F)(F)C(=O)Nc1ccccc1)c1ccccc1C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 2/20 0.43
KCNK9 Q9NPC2 2/20 0.43
PTGS1 P23219 1/20 0.40
CTNNB1 P35222 3/20 0.40
WNT3A P56704 3/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
F2R P25116 1/20 0.39
MAOB P27338 1/20 0.39
PDK1 Q15118 2/20 0.38
PDK2 Q15119 2/20 0.38
PDK3 Q15120 2/20 0.38
PDK4 Q16654 2/20 0.38
PTPRC P08575 1/20 0.38
PTGES O14684 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
KMT2A Q03164 1/20 0.38
SLC1A3 P43003 1/20 0.37
SLC1A2 P43004 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862485 0.86 HPGD (0.46) KCNK3KCNK9GAAPDK1PDK2
SCHEMBL19862481 0.84 KCNK3 (0.46) KCNK3KCNK9LMNAGAAMEN1
SCHEMBL19862491 0.84 KMT2A (0.44) LMNAPDK1PDK2PDK3PDK4
SCHEMBL19865276 0.81 CTNNB1 (0.44) PTGS1CTNNB1WNT3ALMNAGAA
SCHEMBL19865274 0.81 HSD11B1 (0.48) MEN1ALDH1A1KMT2APOLB
SCHEMBL19862480 0.79 KMT2A (0.50) LMNAPDK1PDK2PDK3PDK4
SCHEMBL19862484 0.78 ALDH1A1 (0.42) LMNAMEN1ALDH1A1KMT2A
SCHEMBL19865277 0.77 KMT2A (0.53) KCNK9GAAPDK1PDK2PDK3
SCHEMBL19862670 0.73 SMN1; SMN2 (0.41) KCNK3KCNK9LMNAGAAMEN1
SCHEMBL5332281 0.70 KCNK3 (0.75) KCNK3KCNK9PTGS1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9950999-B2 Non-ionic low diffusing photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 US disclosed
US-9950999-B2 Non-ionic low diffusing photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 US disclosed
US-20180044284-A1 NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed
US-20180044284-A1 NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044284-A1 NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS PLG, PPARG, PKLR KCNK3 618/4885KCNK9 284/4885PTGS1 172/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.