SCHEMBL19862485

SCHEMBL19862485

Cc1ccccc1C(=O)COS(=O)(=O)C(F)(F)C(=O)Nc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.46
ERCC5 P28715 1/20 0.42
FEN1 P39748 1/20 0.42
PDK1 Q15118 2/20 0.41
PDK2 Q15119 2/20 0.41
PDK3 Q15120 2/20 0.41
PDK4 Q16654 2/20 0.41
NOTUM Q6P988 1/20 0.40
ABCC9 O60706 2/20 0.40
ABCC8 Q09428 2/20 0.40
KCNJ11 Q14654 2/20 0.40
KCNJ8 Q15842 2/20 0.40
FFAR1 O14842 1/20 0.39
NPC1 O15118 3/20 0.38
RAB9A P51151 2/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862481 0.86 KCNK3 (0.46) ABCC9ABCC8KCNJ11KCNJ8NPC1
SCHEMBL19862482 0.86 KCNK3 (0.43) PDK1PDK2PDK3PDK4MEN1
SCHEMBL19862491 0.84 KMT2A (0.44) HPGDPDK1PDK2PDK3PDK4
SCHEMBL19862480 0.83 KMT2A (0.50) PDK1PDK2PDK3PDK4NPC1
SCHEMBL19865277 0.79 KMT2A (0.53) PDK1PDK2PDK3PDK4NPC1
SCHEMBL19865274 0.79 HSD11B1 (0.48) NPC1RAB9AMEN1KMT2AALDH1A1
SCHEMBL19862670 0.76 SMN1; SMN2 (0.41) HPGDABCC9ABCC8KCNJ11KCNJ8
SCHEMBL31423406 0.72 ERCC5 (0.49) HPGDERCC5FEN1NPC1RAB9A
SCHEMBL12965356 0.71 PDK1 (0.59) HPGDPDK1PDK2PDK3PDK4
SCHEMBL12813838 0.68 PDK1 (0.54) HPGDPDK1PDK2PDK3PDK4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9950999-B2 Non-ionic low diffusing photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 US disclosed
US-9950999-B2 Non-ionic low diffusing photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 US disclosed
US-20180044284-A1 NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed
US-20180044284-A1 NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS INTERNATIONAL BUSINESS MACHINES CORPORATION 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044284-A1 NON-IONIC LOW DIFFUSING PHOTO-ACID GENERATORS PLG, PPARG, PKLR HPGD 708/4885ERCC5 983/4885FEN1 4572/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.