SCHEMBL19862670

SCHEMBL19862670

C=Cc1ccc(NC(=O)C(F)(F)S(=O)(=O)OCC(=O)c2ccccc2OC)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.41
GBA1 P04062 1/20 0.41
ABCC9 O60706 1/20 0.41
ABCC8 Q09428 1/20 0.41
KCNJ11 Q14654 1/20 0.41
KCNJ8 Q15842 1/20 0.41
KCNK3 O14649 1/20 0.39
KCNK9 Q9NPC2 1/20 0.39
RXFP1 Q9HBX9 1/20 0.38
MAPT P10636 3/20 0.38
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
TP53 P04637 2/20 0.38
LMNA P02545 1/20 0.38
MAPK1 P28482 1/20 0.38
PKM P14618 1/20 0.38
ALDH1A1 P00352 5/20 0.38
KMT2A Q03164 2/20 0.38
HTT P42858 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19862481 0.89 KCNK3 (0.46) SMN1; SMN2GBA1ABCC9ABCC8KCNJ11
SCHEMBL19865185 0.76 L3MBTL1 (0.47) SMN1; SMN2RAB9ANPC1LMNAALDH1A1
SCHEMBL19862485 0.76 HPGD (0.46) SMN1; SMN2ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL19862482 0.73 KCNK3 (0.43) KCNK3KCNK9RXFP1LMNAALDH1A1
SCHEMBL19862488 0.73 CNR2 (0.57) LMNAPKMALDH1A1KMT2AHTT
SCHEMBL12965354 0.72 TGM2 (0.43) SMN1; SMN2ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL19865277 0.72 KMT2A (0.53) SMN1; SMN2KCNK9MAPTRAB9ANPC1
SCHEMBL19862491 0.71 KMT2A (0.44) SMN1; SMN2ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL19862480 0.71 KMT2A (0.50) SMN1; SMN2MAPTRAB9ANPC1LMNA
SCHEMBL19862659 0.70 KMT2A (0.39) SMN1; SMN2ABCC9ABCC8KCNJ11KCNJ8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9951164-B2 Non-ionic aryl ketone based polymeric photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 US disclosed
US-9951164-B2 Non-ionic aryl ketone based polymeric photo-acid generators INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 US disclosed
US-20180044459-A1 NON-IONIC ARYL KETONE BASED POLYMERIC PHOTO-ACID GENERATORS CENTRAL GLASS CO., LTD. (JP) 2018-02-15 US disclosed
US-20180044459-A1 NON-IONIC ARYL KETONE BASED POLYMERIC PHOTO-ACID GENERATORS CENTRAL GLASS CO., LTD. (JP) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180044459-A1 NON-IONIC ARYL KETONE BASED POLYMERIC PHOTO-ACID GENERATORS PPARG, PPARA, PPARD SMN1; SMN2 4519/4885GBA1 3273/4885ABCC9 2303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.